Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | SCN4A | P35499 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.39 |
| ▸ | NCS1 | P62166 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | ILK | Q13418 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.35 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27946280 | 0.86 | EPHX2 (0.44) | EPHX2SCN4ADYRK1ANCS1BACE1 | |
| SCHEMBL5235708 | 0.80 | DYRK1A (0.48) | CLK1DYRK1ANCS1CSNK1DHDAC6 | |
| SCHEMBL147798 | 0.78 | EPHX2 (0.42) | CLK1EPHX2SCN4ADYRK1ABACE1 | |
| SCHEMBL5229957 | 0.77 | DYRK1A (0.42) | CLK1EPHX2SCN4ADYRK1ANCS1 | |
| SCHEMBL25807784 | 0.76 | EPHX2 (0.41) | CLK1EPHX2SCN4ADYRK1ABACE1 | |
| SCHEMBL18002994 | 0.76 | EPHX2 (0.43) | CLK1EPHX2SCN4ADYRK1ABACE1 | |
| SCHEMBL2895393 | 0.74 | CLK1 (0.52) | CLK1DYRK1ANCS1CSNK1DHDAC6 | |
| SCHEMBL17103440 | 0.74 | CLK1 (0.46) | CLK1EPHX2SCN4ADYRK1ANCS1 | |
| SCHEMBL29430298 | 0.74 | CLK1 (0.52) | CLK1DYRK1ANCS1CSNK1DHDAC6 | |
| SCHEMBL18936116 | 0.74 | EPHX2 (0.42) | CLK1EPHX2SCN4ADYRK1ABACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102015641-B | Heterocyclic compound | TAKEDA PHARMACEUTICAL | 2014-01-01 | — | — | CN | disclosed |