Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 2/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | SCN4A | P35499 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5235708 | 0.84 | DYRK1A (0.48) | DYRK1AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5234254 | 0.79 | KMT2A (0.39) | DYRK1AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL153428 | 0.78 | BCL2L1 (0.54) | DYRK1AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL27946277 | 0.77 | CLK1 (0.41) | DYRK1AHDAC6CLK1CSNK1DEPHX2 | |
| SCHEMBL16712270 | 0.76 | CLK1 (0.38) | DYRK1AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5233617 | 0.76 | CYP2A6 (0.53) | DYRK1AHDAC6CHRNA7HTR3ACLK1 | |
| SCHEMBL5163126 | 0.76 | LMNA (0.50) | DYRK1APIM1CYP2C19PPARACLK1 | |
| Isopropylamine SCHEMBL13735900 | 0.74 | BCL2L1 (0.46) | DYRK1AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL30568673 | 0.73 | PTPN2 (0.49) | DYRK1APIM1PIM2HDAC6CHRNA7 | |
| SCHEMBL3879053 | 0.73 | CHRNA7 (0.47) | DYRK1APIM1PIM2HDAC6PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1461335-B1 | 2-HETEROARYLCARBOXYLIC ACID AMIDES | BAYER HEALTHCARE AG (DE) | 2007-02-28 | — | — | EP | disclosed |
| EP-1461335-A1 | 2-HETEROARYLCARBOXYLIC ACID AMIDES | Bayer HealthCare AG (DE) | 2004-09-29 | — | — | EP | disclosed |
| WO-2003055878-A1 | 2-HETEROARYLCARBOXYLIC ACID AMIDES | BAYER HEALTHCARE AG (DE) | 2003-07-10 | — | — | WO | disclosed |