Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 2/20 | 0.75 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.75 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.75 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | STS | P08842 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | PTPRF | P10586 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4544916 | 1.00 | SCN1A (0.75) | SCN1ASCN2ASCN3AMAPTALDH1A1 | |
| SCHEMBL9891376 | 1.00 | SCN1A (0.75) | SCN1ASCN2ASCN3AMAPTALDH1A1 | |
| SCHEMBL25113180 | 0.94 | SCN1A (0.69) | SCN1ASCN2ASCN3AMAPTALDH1A1 | |
| SCHEMBL18641822 | 0.93 | SCN1A (0.67) | SCN1ASCN2ASCN3AMAPTALDH1A1 | |
| SCHEMBL12591313 | 0.93 | SCN1A (0.67) | SCN1ASCN2ASCN3AMAPTALDH1A1 | |
| SCHEMBL13038152 | 0.93 | SCN1A (0.67) | SCN1ASCN2ASCN3AMAPTALDH1A1 | |
| SCHEMBL13038153 | 0.93 | SCN1A (0.67) | SCN1ASCN2ASCN3AMAPTALDH1A1 | |
| SCHEMBL30410127 | 0.92 | SCN1A (0.71) | SCN1ASCN2ASCN3AMAPTALDH1A1 | |
| SCHEMBL12426775 | 0.92 | SCN1A (0.71) | SCN1ASCN2ASCN3AMAPTALDH1A1 | |
| SCHEMBL5014136 | 0.91 | SCN1A (0.65) | SCN1ASCN2ASCN3AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115028529-A | Preparation method of 4-cyclopropyl substituted benzoic acid analogue | 江苏百康德医药科技有限公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-103429079-A | Histone deacetylase inhibitors and compositions and methods of use thereof | CHDI FOUNDATION INC | 2013-12-04 | — | — | CN | disclosed |