Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 2/20 | 0.65 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.65 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.65 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.52 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5014135 | 1.00 | SCN1A (0.65) | SCN1ASCN2ASCN3AF2PRSS1 | |
| SCHEMBL27947110 | 0.91 | SCN1A (0.75) | SCN1ASCN2ASCN3AMAPTALDH1A1 | |
| SCHEMBL4544916 | 0.91 | SCN1A (0.75) | SCN1ASCN2ASCN3AMAPTALDH1A1 | |
| SCHEMBL9891376 | 0.91 | SCN1A (0.75) | SCN1ASCN2ASCN3AMAPTALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL2975912 | 0.90 | SCN1A (0.55) | SCN1ASCN2ASCN3AF2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL2975916 | 0.90 | SCN1A (0.55) | SCN1ASCN2ASCN3AF2PRSS1 | |
| Methane SCHEMBL9812755 | 0.90 | F2 (0.57) | SCN1ASCN2ASCN3AF2PRSS1 | |
| Propane SCHEMBL10482243 | 0.88 | F2 (0.53) | SCN1ASCN2ASCN3AF2PRSS1 | |
| SCHEMBL25113180 | 0.86 | SCN1A (0.69) | SCN1ASCN2ASCN3AMAPTALDH1A1 | |
| SCHEMBL13038153 | 0.85 | SCN1A (0.67) | SCN1ASCN2ASCN3AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1884510-A1 | N-SUBSTITUTED PHENYLACETAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2008-02-06 | — | — | EP | disclosed |