Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | OXTR | P30559 | 1/20 | 0.31 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.30 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL27948632 | 0.96 | KDM4E (0.34) | KDM4EPKMOXTRMCHR2MCHR1 | |
| Iodide SCHEMBL27932889 | 0.96 | KDM4E (0.34) | KDM4EPKMOXTRMCHR2MCHR1 | |
| Hydrochloric Acid SCHEMBL27932978 | 0.96 | KDM4E (0.34) | KDM4EPKMOXTRMCHR2MCHR1 | |
| Bromide SCHEMBL27948695 | 0.85 | KDM4E (0.36) | KDM4EPKMOXTR | |
| Fluoride SCHEMBL27948603 | 0.81 | KDM4E (0.36) | KDM4EPKMOXTR | |
| Hydrochloric Acid SCHEMBL27948785 | 0.81 | KDM4E (0.36) | KDM4EPKMOXTR | |
| Iodide SCHEMBL27948641 | 0.81 | KDM4E (0.36) | KDM4EPKMOXTR | |
| Hydrochloric Acid SCHEMBL28501468 | 0.78 | KDM4E (0.37) | KDM4EPKM | |
| SCHEMBL29033366 | 0.77 | KDM4E (0.33) | KDM4EPKMOXTR | |
| Bromide SCHEMBL27948960 | 0.77 | OXTR (0.33) | KDM4EPKMOXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103509060-A | Metallocene compound, catalyst composite containing metallocene compound and olefin polymerization method using metallocene compound | DAELIM IND CO LTD | 2014-01-15 | — | — | CN | disclosed |