SCHEMBL27948833

SCHEMBL27948833

CC(C)C(CS(=O)(=O)c1ccccc1)OC(=O)c1ccccc1.CCS(=O)(=O)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSIP1 O75475 1/20 0.49
HSD11B1 P28845 4/20 0.41
CA12 O43570 1/20 0.41
CA9 Q16790 1/20 0.41
TP53 P04637 1/20 0.41
TSHR P16473 1/20 0.41
POLB P06746 1/20 0.40
PDCD1 Q15116 1/20 0.40
CD274 Q9NZQ7 1/20 0.40
RAB9A P51151 2/20 0.39
MAPT P10636 1/20 0.39
LMNA P02545 2/20 0.39
NPC1 O15118 1/20 0.39
ALDH1A1 P00352 1/20 0.39
HTT P42858 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
PRKCA P17252 1/20 0.39
GRIA2 P42262 1/20 0.38
GRIA4 P48058 1/20 0.38
MEN1 O00255 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27948832 0.78 MEN1 (0.53) PSIP1HSD11B1CA12CA9TP53
SCHEMBL12863873 0.78 TSHR (0.52) TP53TSHRPOLBPDCD1CD274
SCHEMBL571244 0.76 TSHR (0.53) TP53TSHRPOLBPDCD1CD274
SCHEMBL16044141 0.76 TSHR (0.41) TP53TSHRPOLBPDCD1CD274
SCHEMBL28023643 0.75 HSD11B1 (0.45) PSIP1HSD11B1CA12CA9TP53
SCHEMBL16047777 0.74 TSHR (0.41) TP53TSHRPOLBPDCD1CD274
SCHEMBL24186600 0.73 TSHR (0.50) TP53TSHRPOLBPDCD1CD274
SCHEMBL25982607 0.73 TSHR (0.50) TP53TSHRPOLBPDCD1CD274
SCHEMBL17717443 0.73 TSHR (0.50) TP53TSHRPOLBPDCD1CD274
SCHEMBL14690196 0.73 TSHR (0.53) TP53TSHRPOLBPDCD1CD274

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103509135-A Olefin polymerization catalyst component, preparation method and application thereof CHINA PETROLEUM & CHEMICAL 2014-01-15 CN disclosed