Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.52 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | F7 | P08709 | 1/20 | 0.50 |
| ▸ | F3 | P13726 | 1/20 | 0.50 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.50 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.50 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.50 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.50 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22426419 | 0.81 | ALDH1A1 (0.56) | HPGDALDH1A1APPGAAHCAR3 | |
| SCHEMBL7289960 | 0.81 | AKR1C3 (0.66) | ALDH1A1APPGAAHCAR3HCAR2 | |
| SCHEMBL6950942 | 0.79 | GAA (0.65) | HPGDALDH1A1APPGAAHCAR3 | |
| SCHEMBL6770549 | 0.79 | HPGD (0.59) | HPGDALDH1A1APPGAAHCAR3 | |
| SCHEMBL3251235 | 0.79 | ALDH1A1 (0.52) | HPGDALDH1A1APPGAAHCAR3 | |
| SCHEMBL11637980 | 0.79 | ATM (0.59) | ALDH1A1APPGAAHCAR3HCAR2 | |
| SCHEMBL29913321 | 0.79 | AKR1C3 (0.61) | ALDH1A1GAAKMT2APOLB | |
| SCHEMBL723657 | 0.79 | AKR1C3 (0.61) | ALDH1A1GAAKMT2APOLB | |
| SCHEMBL1242243 | 0.79 | ALDH1A1 (0.71) | ALDH1A1APPGAAHCAR3HCAR2 | |
| SCHEMBL29915528 | 0.79 | ALDH1A1 (0.71) | ALDH1A1APPGAAHCAR3HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103626693-A | A class of pleuromytilin derivatives, drug composition, synthesis methods and uses thereof | SHANGHAI INST MATERIA MEDICA | 2014-03-12 | — | — | CN | disclosed |