SCHEMBL27952945

SCHEMBL27952945

Cc1ccc(Cl)c(C)c1Br

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.36
ALDH1A1 P00352 2/20 0.36
MAPT P10636 1/20 0.34
CES1 P23141 2/20 0.32
S1PR1 P21453 1/20 0.32
HTR2C P28335 1/20 0.32
RAPGEF4 Q8WZA2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15218472 0.83 ALDH1A1 (0.39) ALDH1A1MAPTCES1
SCHEMBL4448674 0.81 CYP3A4 (0.37) CYP3A4ALDH1A1CES1S1PR1
SCHEMBL8762239 0.79 ALDH1A1 (0.41) ALDH1A1MAPTCES1
SCHEMBL21459542 0.79 NCEH1 (0.37) CYP3A4ALDH1A1MAPTCES1S1PR1
SCHEMBL19830027 0.79 CYP3A4 (0.36) CYP3A4ALDH1A1CES1S1PR1HTR2C
SCHEMBL10753626 0.77 NCEH1 (0.42) ALDH1A1
SCHEMBL15476296 0.75 CYP3A4 (0.42) CYP3A4ALDH1A1MAPT
SCHEMBL22162367 0.75 HTR2A (0.35) CYP3A4CES1S1PR1HTR2CRAPGEF4
SCHEMBL31483102 0.75 HTR2A (0.35) CYP3A4CES1S1PR1HTR2CRAPGEF4
SCHEMBL31483105 0.75 HTR2A (0.35) CYP3A4CES1S1PR1HTR2CRAPGEF4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102395546-B Method for producing aromatic chlorine and bromine compounds BAYER CROPSCIENCE AG 2014-03-12 CN disclosed