Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.57 |
| ▸ | MEN1 | O00255 | 7/20 | 0.57 |
| ▸ | ATM | Q13315 | 4/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | PDE5A | O76074 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5394457 | 0.73 | MEN1 (0.69) | KMT2AMEN1ATMHSP90AA1KDM4E | |
| SCHEMBL29733244 | 0.71 | FABP3 (0.49) | KMT2AKDM4EGAAALDH1A1LMNA | |
| SCHEMBL35121 | 0.71 | FABP3 (0.49) | KMT2AKDM4EGAAALDH1A1LMNA | |
| SCHEMBL10871851 | 0.71 | THRB (0.51) | KMT2AMEN1KDM4EALDH1A1HTT | |
| SCHEMBL30007447 | 0.71 | THRB (0.51) | KMT2AMEN1KDM4EALDH1A1HTT | |
| Biphenyl SCHEMBL27827806 | 0.70 | FABP3 (0.48) | KMT2AKDM4EGAAALDH1A1LMNA | |
| SCHEMBL12495092 | 0.70 | PDE5A (1.00) | ATMPDE5AL3MBTL1NR3C2GLA | |
| SCHEMBL11206659 | 0.69 | MEN1 (0.66) | KMT2AMEN1ATMHSP90AA1KDM4E | |
| SCHEMBL23052404 | 0.68 | MEN1 (0.73) | KMT2AMEN1ATMHSP90AA1KDM4E | |
| SCHEMBL14338087 | 0.68 | MEN1 (0.69) | KMT2AMEN1ATMHSP90AA1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103601679-B | Reduced glutathione fluorescent probe with pyrazoline as maternal body | UNIV SHANDONG | 2015-04-22 | — | — | CN | disclosed |
| CN-103601679-A | Reduced glutathione fluorescent probe with pyrazoline as maternal body | UNIV SHANDONG | 2014-02-26 | — | — | CN | disclosed |