Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.95 |
| ▸ | TP53 | P04637 | 4/20 | 0.95 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.95 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.95 |
| ▸ | LMNA | P02545 | 3/20 | 0.95 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.95 |
| ▸ | NPC1 | O15118 | 3/20 | 0.95 |
| ▸ | RAB9A | P51151 | 3/20 | 0.95 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.95 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.95 |
| ▸ | THPO | P40225 | 2/20 | 0.95 |
| ▸ | GMNN | O75496 | 2/20 | 0.95 |
| ▸ | MTOR | P42345 | 2/20 | 0.95 |
| ▸ | BLM | P54132 | 2/20 | 0.95 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.95 |
| ▸ | PPM1B | O75688 | 1/20 | 0.95 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.95 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.95 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.95 |
| ▸ | PPP5C | P53041 | 1/20 | 0.95 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cantharidin SCHEMBL152261 | 0.98 | MAPK1 (1.00) | MAPK1TP53CYP3A4HIF1ALMNA | |
| Cantharidin SCHEMBL152262 | 0.98 | MAPK1 (1.00) | MAPK1TP53CYP3A4HIF1ALMNA | |
| Cantharidin SCHEMBL1805181 | 0.98 | MAPK1 (1.00) | MAPK1TP53CYP3A4HIF1ALMNA | |
| Cantharidin SCHEMBL14120808 | 0.98 | MAPK1 (1.00) | MAPK1TP53CYP3A4HIF1ALMNA | |
| Cantharidin SCHEMBL27034990 | 0.95 | MAPK1 (0.95) | MAPK1TP53CYP3A4HIF1ALMNA | |
| Cantharidin SCHEMBL27972121 | 0.95 | MAPK1 (0.95) | MAPK1TP53CYP3A4HIF1ALMNA | |
| Cantharidin SCHEMBL27965964 | 0.95 | MAPK1 (0.95) | MAPK1TP53CYP3A4HIF1ALMNA | |
| Cantharidin SCHEMBL27817827 | 0.95 | MAPK1 (0.95) | MAPK1TP53CYP3A4HIF1ALMNA | |
| Cantharidin SCHEMBL27879561 | 0.88 | MAPK1 (0.81) | MAPK1TP53CYP3A4HIF1ALMNA | |
| SCHEMBL20885000 | 0.82 | MAPK1 (0.71) | MAPK1TP53CYP3A4HIF1ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103923095-A | Demethylated calcium cantharidate | UNIV ZUNYI MEDICAL | 2014-07-16 | — | — | CN | disclosed |