Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.52 |
| ▸ | PPARD | Q03181 | 3/20 | 0.52 |
| ▸ | PPARA | Q07869 | 3/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 9/20 | 0.41 |
| ▸ | MAOB | P27338 | 9/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15897863 | 0.86 | HRH3 (0.56) | PPARGPPARDPPARAHRH3APP | |
| SCHEMBL15880148 | 0.82 | HRH3 (0.48) | PPARGPPARDPPARAHRH3PARP1 | |
| SCHEMBL15880025 | 0.82 | HRH3 (0.58) | PPARGPPARDPPARAHRH3PARP1 | |
| SCHEMBL19675654 | 0.82 | HRH3 (0.49) | PPARGPPARDPPARAHRH3MAOA | |
| Hydrochloric Acid SCHEMBL1426687 | 0.81 | HRH3 (0.47) | PPARGPPARDPPARAHRH3PARP1 | |
| SCHEMBL30025932 | 0.80 | HTR2C (0.50) | HRH3SMN1; SMN2 | |
| SCHEMBL550150 | 0.80 | HTR2C (0.50) | HRH3SMN1; SMN2 | |
| SCHEMBL19675471 | 0.78 | HRH3 (0.45) | PPARGPPARDPPARAHRH3APP | |
| SCHEMBL28039297 | 0.78 | HRH3 (0.51) | PPARGPPARDPPARAHRH3MAOA | |
| SCHEMBL4762185 | 0.77 | HRH3 (0.60) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103764143-B | Lipoxygenase inhibitors | 斯坦福国际咨询研究所 | 2017-05-03 | — | — | CN | disclosed |
| CN-103764143-A | Lipoxygenase inhibitors | STANFORD RES INST INT | 2014-04-30 | — | — | CN | disclosed |