Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | HTR5A | P47898 | 2/20 | 0.46 |
| ▸ | CPS1 | P31327 | 1/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | DRD5 | P21918 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30025932 | 1.00 | HTR2C (0.50) | HTR2CHTR2AHTR2BHTR5ACPS1 | |
| Acetic Acid SCHEMBL10992625 | 0.90 | CPS1 (0.48) | HTR2CHTR2AHTR2BHTR5ACPS1 | |
| SCHEMBL30471897 | 0.89 | HRH3 (0.52) | HTR2CHTR2AHTR2BHTR5APDE3B | |
| SCHEMBL1395133 | 0.89 | HRH3 (0.52) | HTR2CHTR2AHTR2BHTR5APDE3B | |
| SCHEMBL1248073 | 0.87 | PPARG (0.49) | HTR2CHTR2AHTR2BHTR5APDE3B | |
| SCHEMBL565913 | 0.85 | DRD2 (0.53) | HTR2CHTR2AHTR2BPDE3BPDE3A | |
| SCHEMBL21635492 | 0.84 | EIF2AK2 (0.47) | CPS1DRD2GFERSMN1; SMN2HRH3 | |
| SCHEMBL5999174 | 0.83 | PDE3B (0.59) | HTR2CHTR2AHTR2BHTR5APDE3B | |
| Hydrochloric Acid SCHEMBL2208190 | 0.83 | DRD2 (0.52) | HTR2CHTR2AHTR2BPDE3BPDE3A | |
| Hydrochloric Acid SCHEMBL2208192 | 0.83 | DRD2 (0.52) | HTR2CHTR2AHTR2BPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117229275-B | Novel 2-acetamido thiazole compound and preparation method and application thereof | 北京中医药大学 | 2024-06-18 | — | — | CN | claimed |
| US-20260085077-A1 | HETEROCYCLIC DERIVATIVES AS JANUS KINASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2026-03-26 | — | — | US | disclosed |
| US-20250304567-A1 | PYRROLIDIONE DERIVATIVES AS INHIBITORS OF NF KAPPA B INDUCING KINASE | JANSSEN PHARMACEUTICA NV (BE) | 2025-10-02 | — | — | US | disclosed |
| EP-4583977-A1 | HETEROCYCLIC DERIVATIVES AS JANUS KINASE INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2025-07-16 | — | — | EP | disclosed |
| EP-4581028-A1 | INDOLINE DERIVATIVES AS SEROTONERGIC AGENTS USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | Mindset Pharma Inc. (CA) | 2025-07-09 | — | — | EP | disclosed |
| CN-119822910-A | Method for catalyzing heterogeneous reduction of nitrogen-containing heterocyclic compound by using magnesium metal | 延安大学 | 2025-04-15 | — | — | CN | disclosed |
| US-12220421-B2 | Inhibitors of C. difficile spore germination | THE BOARDS OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS (US) | 2025-02-11 | — | — | US | disclosed |
| WO-2024163852-A1 | HISTIDINE KINASE INHIBITORS AS ANTIBACTERIAL AGENTS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2024-08-08 | — | — | WO | disclosed |
| EP-4398890-A2 | INHIBITORS OF C. DIFFICILE SPORE GERMINATION | Abel-Santos, Ernesto (US) | 2024-07-17 | — | — | EP | disclosed |
| US-20240199607-A1 | BICYCLIC HETEROCYCLE COMPOUNDS AND THEIR USES IN THERAPY | ASTEX THERAPEUTICS LIMITED (GB) | 2024-06-20 | — | — | US | disclosed |
| WO-1995023141-A1 | 4-HETEROCYCLYL-SUBSTITUTED QUINAZOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS ANTI-CANCER AGENTS | PFIZER INC. (US) | 1995-08-31 | — | — | WO | disclosed |
| US-4496492-A | Substituted phenylalkyl compounds | THE UPJOHN COMPANY (US) | 1985-01-29 | — | — | US | disclosed |
| US-4431820-A | BACTERICIDES; ANTIBIOTICS | THE UPJOHN COMPANY (US) | 1984-02-14 | — | — | US | disclosed |
| US-4424365-A | 1,2,8,8a-Cyclopropa c!benzo 1,2,-b:-4,3-b'!dipyrrol-4(5H)-ones | THE UPJOHN COMPANY (US) | 1984-01-03 | — | — | US | disclosed |
| US-4423230-A | REACTING A 5-HYDROXY BENZO(1,2-B: 3,4-B')DIPYRROLE WITH TRIPHENYLPHOSPHINE AND CARBONTETRAHALIDE OR N-IODOSUCCINIMIDE | THE UPJOHN COMPANY (US) | 1983-12-27 | — | — | US | disclosed |
| US-4423228-A | CYCLIZATION OF ALCOHOL, TRIPHENYLPHOSPHINE, CARBON TETRAHALIDE | THE UPJOHN COMPANY (US) | 1983-12-27 | — | — | US | disclosed |
| US-4423229-A | Composition of matter and process | THE UPJOHN COMPANY (US) | 1983-12-27 | — | — | US | disclosed |
| US-4413132-A | Antibiotic CC-1065 indoline intermediates | THE UPJOHN COMPANY (US) | 1983-11-01 | — | — | US | disclosed |
| US-4400518-A | Composition of matter and process | THE UPJOHN COMPANY (US) | 1983-08-23 | — | — | US | disclosed |
| US-4159271-A | CYCLIZATION OF A 2-HALOGENOPHENETHYLAMINE | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 1979-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250304567-A1 | PYRROLIDIONE DERIVATIVES AS INHIBITORS OF NF KAPPA B INDUCING KINASE | NFKBIA, IKBKG, IKBKB | HTR2C 4879/4885HTR2A 4877/4885HTR2B 4875/4885 |
| US-12220421-B2 | Inhibitors of C. difficile spore germination | CDC37, SI, DAD1 | HTR2C 2959/4885HTR2A 3318/4885HTR2B 2591/4885 |
| US-20240199607-A1 | BICYCLIC HETEROCYCLE COMPOUNDS AND THEIR USES IN THERAPY | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CCNB1, CCNE1 | HTR2C 2658/4885HTR2A 3085/4885HTR2B 848/4885 |
| US-20260085077-A1 | HETEROCYCLIC DERIVATIVES AS JANUS KINASE INHIBITORS | TYK2, JAK1, JAK3 | HTR2C 799/4885HTR2A 2400/4885HTR2B 3219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.