Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 8/20 | 0.39 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27957178 | 0.79 | QPCT (0.46) | QPCT | |
| SCHEMBL27957165 | 0.74 | QPCT (0.43) | QPCTIP6K1CCR5 | |
| SCHEMBL1444262 | 0.74 | QPCT (0.52) | QPCTIP6K1 | |
| SCHEMBL28811970 | 0.72 | QPCT (0.41) | QPCTIP6K1CCR5 | |
| SCHEMBL1673469 | 0.71 | NUDT1 (0.46) | QPCTIP6K1CCR5 | |
| SCHEMBL29445215 | 0.68 | QPCT (0.52) | QPCTIP6K1 | |
| SCHEMBL29445191 | 0.68 | QPCT (0.52) | QPCTIP6K1 | |
| SCHEMBL20853792 | 0.68 | QPCT (0.52) | QPCTIP6K1 | |
| SCHEMBL21373482 | 0.68 | QPCT (0.40) | QPCTIP6K1CCR5 | |
| SCHEMBL1444543 | 0.68 | QPCT (0.72) | QPCT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102695546-B | Heterocylcic derivatives as inhibitors of glutaminyl cyclase | PROBIODRUG AG | 2014-09-10 | — | — | CN | claimed |