SCHEMBL27957232

SCHEMBL27957232

O=C(CCc1ccccc1Br)OCc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.53
MAPK1 P28482 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
FFAR4 Q5NUL3 2/20 0.49
FFAR1 O14842 1/20 0.49
KDM4E B2RXH2 1/20 0.45
HPGD P15428 1/20 0.45
NPY1R P25929 1/20 0.45
NPY2R P49146 1/20 0.45
CYP4F2 P78329 1/20 0.45
CYP4A11 Q02928 1/20 0.45
SLC6A2 P23975 1/20 0.45
SLC6A3 Q01959 1/20 0.45
KMT2A Q03164 1/20 0.45
LMNA P02545 1/20 0.45
THRA P10827 1/20 0.44
THRB P10828 1/20 0.44
TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7062295 0.85 FFAR4 (0.47) ALDH1A1MAPK1L3MBTL1TDP1FFAR4
SCHEMBL28662041 0.83 TDP1 (0.54) ALDH1A1MAPK1L3MBTL1TDP1CYP4F2
SCHEMBL304176 0.81 TDP1 (0.78) ALDH1A1MAPK1L3MBTL1TDP1FFAR4
SCHEMBL24405103 0.81 ALDH1A1 (0.53) ALDH1A1MAPK1L3MBTL1TDP1HPGD
SCHEMBL306178 0.81 ALDH1A1 (0.53) ALDH1A1MAPK1L3MBTL1TDP1KDM4E
SCHEMBL24405114 0.81 ALDH1A1 (0.53) ALDH1A1MAPK1L3MBTL1TDP1FFAR1
SCHEMBL1511313 0.81 CYP4F2 (0.69) ALDH1A1TDP1KDM4ECYP4F2CYP4A11
SCHEMBL7061717 0.80 FFAR4 (0.43) ALDH1A1MAPK1L3MBTL1TDP1FFAR4
SCHEMBL7061719 0.80 FFAR4 (0.43) ALDH1A1MAPK1L3MBTL1TDP1FFAR4
Ammonia Solution, Strong SCHEMBL28588274 0.80 TDP1 (0.75) ALDH1A1MAPK1L3MBTL1TDP1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105198692-A Method for asymmetrically catalyzing and synthesizing (S)-curcumene UNIV CHINA AGRICULTURAL 2015-12-30 CN disclosed
CN-105198722-A Method for asymmetrically catalyzing and synthesizing (R)-4, 7-dimethyl-1-tetralone UNIV CHINA AGRICULTURAL 2015-12-30 CN disclosed
CN-103755553-B Novel asymmetric catalytic synthesis method of (S)-naproxen UNIV CHINA AGRICULTURAL 2015-02-18 CN disclosed
CN-103755554-B Novel method for asymmetric catalytic synthesis of (S)-fenoprofen UNIV CHINA AGRICULTURAL 2015-02-18 CN disclosed
CN-103755554-A Novel method for asymmetric catalytic synthesis of (S)-fenoprofen UNIV CHINA AGRICULTURAL 2014-04-30 CN disclosed
CN-103755553-A Novel asymmetric catalytic synthesis method of (S)-naproxen UNIV CHINA AGRICULTURAL 2014-04-30 CN disclosed
CN-103755566-A Novel method for asymmetric catalytic synthesis of (S)-2-aryl propionate UNIV CHINA AGRICULTURAL 2014-04-30 CN disclosed