Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 9/20 | 0.35 |
| ▸ | KDR | P35968 | 9/20 | 0.35 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30230974 | 0.84 | MAPK1 (0.35) | MAPK1FLT1KDRGPR52CCNC | |
| SCHEMBL22125797 | 0.81 | MAPK1 (0.39) | MAPK1FLT1KDRCCNCCDK8 | |
| SCHEMBL28539426 | 0.80 | FLT1 (0.36) | MAPK1FLT1KDRCCNCCDK8 | |
| SCHEMBL5496670 | 0.79 | HASPIN (0.38) | MAPK1FLT1KDRCCNCCDK8 | |
| SCHEMBL4327167 | 0.79 | NR3C2 (0.47) | MAPK1FLT1KDRCCNCCDK8 | |
| SCHEMBL22125615 | 0.78 | MAPK1 (0.37) | MAPK1FLT1KDRCCNCCDK8 | |
| SCHEMBL22125767 | 0.77 | ALDH1A1 (0.41) | MAPK1FLT1KDRALDH1A1SMN1; SMN2 | |
| SCHEMBL22125846 | 0.77 | FLT1 (0.40) | MAPK1FLT1KDRCCNCCDK8 | |
| SCHEMBL30282550 | 0.76 | ALDH1A1 (0.40) | MAPK1FLT1KDRALDH1A1SMN1; SMN2 | |
| SCHEMBL22125776 | 0.75 | MAPK1 (0.38) | MAPK1FLT1KDRCCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103819405-A | Method for preparing N-(1-(2-formyloxy ethyl)-1H-pyrazole-5-base) formamide | WANG XIANGSHAN | 2014-05-28 | — | — | CN | claimed |