SCHEMBL27959403

SCHEMBL27959403

CO[Si](O)(O)Cc1cc(F)cc(F)c1

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.39
CYP4F2 P78329 1/20 0.33
CYP4A11 Q02928 1/20 0.33
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA9 Q16790 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
CLK1 P49759 1/20 0.31
CLK2 P49760 1/20 0.31
DYRK1A Q13627 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15738500 0.83 IDO1 (0.39) IDO1CYP4F2CYP4A11CA12CA1
SCHEMBL15736814 0.82 MAOB (0.36)
SCHEMBL15737727 0.81 IDO1 (0.46) IDO1
SCHEMBL15735694 0.80 IDO1 (0.36) IDO1CYP4F2CYP4A11CA12CA1
SCHEMBL15734011 0.79 IDO1 (0.39) IDO1
SCHEMBL15736396 0.78 IDO1 (0.41) IDO1CYP4F2CYP4A11MEN1KMT2A
SCHEMBL15734346 0.78 TAAR1 (0.33)
SCHEMBL15738014 0.77 IDO1 (0.34) IDO1CYP4F2CYP4A11MEN1KMT2A
SCHEMBL15737885 0.77 IDO1 (0.40) IDO1CYP4F2CYP4A11MEN1KMT2A
SCHEMBL15736561 0.76 TRPV1 (0.35) IDO1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103848859-A Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing same SHINETSU CHEMICAL CO 2014-06-11 CN disclosed