Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 9/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 9/20 | 0.39 |
| ▸ | PI4KA | P42356 | 1/20 | 0.34 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.34 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL130453 | 0.75 | ADORA1 (0.60) | FDPSP2RX7HDAC6FGFR1FGFR4 | |
| SCHEMBL30572667 | 0.75 | ADORA1 (0.60) | FDPSP2RX7HDAC6FGFR1FGFR4 | |
| SCHEMBL26348841 | 0.75 | FDPS (0.44) | FDPSP2RX7HDAC6FGFR1FGFR4 | |
| SCHEMBL11908593 | 0.75 | ADORA2A (0.60) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL1868819 | 0.75 | FDPS (0.44) | FDPSP2RX7HDAC6FGFR1FGFR4 | |
| SCHEMBL28003435 | 0.73 | FDPS (0.43) | FDPSP2RX7HDAC6FGFR1FGFR4 | |
| SCHEMBL6670287 | 0.72 | FDPS (0.42) | FDPSP2RX7HDAC6FGFR1FGFR4 | |
| SCHEMBL23323404 | 0.71 | FDPS (0.63) | FDPSP2RX7HDAC6FGFR1FGFR4 | |
| SCHEMBL20964641 | 0.71 | FDPS (0.41) | FDPSP2RX7HDAC6FGFR1FGFR4 | |
| SCHEMBL7832523 | 0.71 | ADORA2A (0.64) | FDPSP2RX7HDAC6FGFR1FGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108358927-A | 1,4- bis- replaces 1,2,3- ribavirin analogs and its preparation method and application | 郑州大学 | 2018-08-03 | — | — | CN | claimed |
| CN-105130989-B | A kind of 2 fluoroadenine synthetic methods | 新乡学院 | 2017-10-03 | — | — | CN | claimed |
| CN-105130989-A | 2-fluoroadenine synthetic method | UNIV XINXIANG | 2015-12-09 | — | — | CN | claimed |
| CN-110283174-A | A kind of PI3K δ inhibitor and application thereof | 安徽中医药大学 | 2019-09-27 | — | — | CN | disclosed |
| CN-106582579-B | The miscellaneous cup of four chomene [2] aromatic hydrocarbons [2] triazine bonded silica gel stationary phase and its preparation method and application | 郑州大学 | 2019-07-02 | — | — | CN | disclosed |
| CN-108358927-A | 1,4- bis- replaces 1,2,3- ribavirin analogs and its preparation method and application | 郑州大学 | 2018-08-03 | — | — | CN | disclosed |
| CN-107573346-A | N9 is alkylated the simple synthesis of nucleoside analog on a kind of purine skeleton | 华南理工大学 | 2018-01-12 | — | — | CN | disclosed |
| CN-107236016-A | It is a kind of to contain steroidal purine nucleoside analogs of 1,2,3 triazoles and its preparation method and application | 郑州大学 | 2017-10-10 | — | — | CN | disclosed |
| CN-105130989-B | A kind of 2 fluoroadenine synthetic methods | 新乡学院 | 2017-10-03 | — | — | CN | disclosed |
| CN-106582579-A | Four-oxygen naphthalene mixed cup [2] arene [2] triazine bonded silica gel stationary phase and preparation method and application thereof | 郑州大学 | 2017-04-26 | — | — | CN | disclosed |
| CN-105130989-A | 2-fluoroadenine synthetic method | UNIV XINXIANG | 2015-12-09 | — | — | CN | disclosed |
| CN-104945420-A | Pyrimidinones as PI3K inhibitors | INCYTE CORP | 2015-09-30 | — | — | CN | disclosed |
| CN-102482278-B | Pyrimidinones as PI3K inhibitors | INCYTE CORP | 2015-04-22 | — | — | CN | disclosed |
| CN-102659785-B | 2-amino-6-aminomethylpurine compound and preparation method and application thereof | UNIV SHANDONG | 2014-04-30 | — | — | CN | disclosed |
| CN-102229609-A | Quinazolinones as inhibitors of human phosphatidylinositol 3-kinase delta | ICOS CORP | 2011-11-02 | — | — | CN | disclosed |
| CN-101031569-A | Quinazolinones as human phosphatidylinositol 3-kinase delta inhibitors | ICOS CORP (US) | 2007-09-05 | — | — | CN | disclosed |