SCHEMBL2796496

SCHEMBL2796496

CO[Si](CCCN1CCCCCC1=O)(OC)OC

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.43
PGK1 P00558 1/20 0.42
KMT2A Q03164 3/20 0.41
MEN1 O00255 1/20 0.41
NPC1 O15118 1/20 0.40
ATM Q13315 1/20 0.40
POLB P06746 1/20 0.40
ALDH1A1 P00352 2/20 0.40
RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4195239 0.98 SMN1; SMN2 (0.45) SMN1; SMN2L3MBTL1PGK1KMT2AMEN1
SCHEMBL4209182 0.95 SMN1; SMN2 (0.43) SMN1; SMN2L3MBTL1PGK1KMT2AMEN1
SCHEMBL4198847 0.94 SMN1; SMN2 (0.44) SMN1; SMN2L3MBTL1PGK1KMT2AMEN1
SCHEMBL2798224 0.94 SMN1; SMN2 (0.49) SMN1; SMN2L3MBTL1PGK1KMT2ANPC1
SCHEMBL4197250 0.89 SMN1; SMN2 (0.48) SMN1; SMN2L3MBTL1PGK1KMT2ANPC1
SCHEMBL9155200 0.86 SMN1; SMN2 (0.41) SMN1; SMN2L3MBTL1PGK1KMT2AMEN1
SCHEMBL2798086 0.85 SMN1; SMN2 (0.42) SMN1; SMN2L3MBTL1PGK1KMT2AMEN1
SCHEMBL8088805 0.83 KMT2A (0.47) SMN1; SMN2L3MBTL1PGK1KMT2AMEN1
SCHEMBL4199141 0.83 SMN1; SMN2 (0.43) SMN1; SMN2L3MBTL1PGK1KMT2AMEN1
SCHEMBL4200346 0.81 SMN1; SMN2 (0.41) SMN1; SMN2L3MBTL1PGK1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8071682-B2 Method for producing conjugated diene polymer, conjugated diene polymer, and polymer composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-06 US claimed
US-7750087-B2 Modified polymers prepared with lanthanide-based catalysts BRIDGESTONE CORPORATION (JP) 2010-07-06 US claimed
US-20090005496-A1 METHOD FOR PRODUCING CONJUGATED DIENE POLYMER, CONJUGATED DIENE POLYMER, AND POLYMER COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-01-01 US claimed
US-20060030677-A1 Prepared by polymerizing conjugated monomer with a lanthanide-based catalyst to form a pseudo-living polymer and reacting the polymer with a di- or trihydrocarbyloxysilane having a reactive functional group such as (meth)acrylate, epoxy, or isocyanate that forms a chemical bond with the polymer; curable ENEOS MATERIALS CORPORATION (JP) 2006-02-09 US claimed
US-6992147-B1 Modified polymers prepared with lanthanide-based catalysts BRIDGESTONE CORPORATION (JP) 2006-01-31 US claimed
EP-0413520-B1 A silane compound and a method of manufacturing the same SHINETSU CHEMICAL CO (JP) 1995-03-01 EP claimed
US-5116973-A CAPROLACTAM SILANE COMPOUND AND A METHOD OF MANUFACTURING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 1992-05-26 US claimed
EP-0413520-A2 A silane compound and a method of manufacturing the same Shin-Etsu Chemical Co., Ltd. (JP) 1991-02-20 EP claimed
JP-3074392-A None JP disclosed
US-8071682-B2 Method for producing conjugated diene polymer, conjugated diene polymer, and polymer composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-06 US disclosed
US-7750087-B2 Modified polymers prepared with lanthanide-based catalysts BRIDGESTONE CORPORATION (JP) 2010-07-06 US disclosed
EP-1230273-B1 MODIFIED POLYMERS PREPARED WITH LANTHANIDE-BASED CATALYSTS BRIDGESTONE CORP (JP) 2009-02-11 EP disclosed
US-20090005496-A1 METHOD FOR PRODUCING CONJUGATED DIENE POLYMER, CONJUGATED DIENE POLYMER, AND POLYMER COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-01-01 US disclosed
US-20060030677-A1 Prepared by polymerizing conjugated monomer with a lanthanide-based catalyst to form a pseudo-living polymer and reacting the polymer with a di- or trihydrocarbyloxysilane having a reactive functional group such as (meth)acrylate, epoxy, or isocyanate that forms a chemical bond with the polymer; curable ENEOS MATERIALS CORPORATION (JP) 2006-02-09 US disclosed
EP-1230273-A1 MODIFIED POLYMERS PREPARED WITH LANTHANIDE-BASED CATALYSTS Bridgestone Corporation (JP) 2002-08-14 EP disclosed
WO-2001034658-A1 MODIFIED POLYMERS PREPARED WITH LANTHANIDE-BASED CATALYSTS BRIDGESTONE CORPORATION (JP) 2001-05-17 WO disclosed
EP-0413520-B1 A silane compound and a method of manufacturing the same SHINETSU CHEMICAL CO (JP) 1995-03-01 EP disclosed
US-5116973-A CAPROLACTAM SILANE COMPOUND AND A METHOD OF MANUFACTURING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 1992-05-26 US disclosed
JP-H0374392-A SILANE COMPOUND AND PRODUCTION THEREOF SHIN ETSU CHEM CO LTD 1991-03-28 JP disclosed
EP-0413520-A2 A silane compound and a method of manufacturing the same Shin-Etsu Chemical Co., Ltd. (JP) 1991-02-20 EP disclosed