Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | PGK1 | P00558 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9117207 | 0.94 | SMN1; SMN2 (0.45) | SMN1; SMN2KMT2AL3MBTL1RAB9APGK1 | |
| SCHEMBL2796496 | 0.86 | SMN1; SMN2 (0.44) | SMN1; SMN2KMT2AMEN1L3MBTL1RAB9A | |
| SCHEMBL9154923 | 0.85 | SMN1; SMN2 (0.41) | SMN1; SMN2KMT2AMEN1L3MBTL1RAB9A | |
| SCHEMBL4195239 | 0.84 | SMN1; SMN2 (0.45) | SMN1; SMN2KMT2AMEN1L3MBTL1RAB9A | |
| SCHEMBL4209182 | 0.82 | SMN1; SMN2 (0.43) | SMN1; SMN2KMT2AMEN1L3MBTL1RAB9A | |
| SCHEMBL4198847 | 0.80 | SMN1; SMN2 (0.44) | SMN1; SMN2KMT2AMEN1L3MBTL1RAB9A | |
| SCHEMBL2798224 | 0.80 | SMN1; SMN2 (0.49) | SMN1; SMN2KMT2AL3MBTL1RAB9APGK1 | |
| SCHEMBL9117135 | 0.79 | SMN1; SMN2 (0.45) | SMN1; SMN2KMT2AMEN1L3MBTL1RAB9A | |
| SCHEMBL2798086 | 0.78 | SMN1; SMN2 (0.42) | SMN1; SMN2KMT2AMEN1L3MBTL1RAB9A | |
| SCHEMBL9157289 | 0.76 | KMT2A (0.39) | SMN1; SMN2KMT2AMEN1L3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413520-B1 | A silane compound and a method of manufacturing the same | SHINETSU CHEMICAL CO (JP) | 1995-03-01 | — | — | EP | claimed |
| US-5116973-A | CAPROLACTAM SILANE COMPOUND AND A METHOD OF MANUFACTURING THE SAME | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1992-05-26 | — | — | US | claimed |
| EP-0413520-B1 | A silane compound and a method of manufacturing the same | SHINETSU CHEMICAL CO (JP) | 1995-03-01 | — | — | EP | disclosed |
| US-5116973-A | CAPROLACTAM SILANE COMPOUND AND A METHOD OF MANUFACTURING THE SAME | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1992-05-26 | — | — | US | disclosed |