Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.34 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | KHK | P50053 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30881787 | 0.75 | TRPV4 (0.39) | TRPV4VCAM1KDM4EALDH1A1MAOA | |
| SCHEMBL29209743 | 0.75 | TRPV4 (0.39) | TRPV4VCAM1KDM4EALDH1A1MAOA | |
| SCHEMBL28327553 | 0.75 | TRPV4 (0.39) | TRPV4VCAM1ALDH1A1AR | |
| SCHEMBL6739076 | 0.75 | TRPV4 (0.39) | TRPV4VCAM1CSNK1A1CLK4IDO1 | |
| SCHEMBL31636812 | 0.75 | TRPV4 (0.39) | TRPV4VCAM1ALDH1A1AR | |
| SCHEMBL2657089 | 0.75 | TRPV4 (0.39) | TRPV4KDM4EUSP2ALDH1A1MAOA | |
| SCHEMBL28245840 | 0.74 | TRPV4 (0.42) | TRPV4VCAM1CSNK1A1CLK4IDO1 | |
| SCHEMBL30352797 | 0.74 | KDM4E (0.43) | TRPV4CSNK1A1CLK4KDM4EUSP2 | |
| SCHEMBL28597079 | 0.74 | KDM4E (0.43) | TRPV4CSNK1A1CLK4KDM4EUSP2 | |
| SCHEMBL18341359 | 0.71 | HTT (0.36) | TRPV4KDM4EUSP2ALDH1A1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103842341-A | Novel estrogen receptor ligands | KAROBIO AB | 2014-06-04 | — | — | CN | disclosed |