Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.79 |
| ▸ | TP53 | P04637 | 2/20 | 0.79 |
| ▸ | PNP | P00491 | 1/20 | 0.79 |
| ▸ | HTT | P42858 | 1/20 | 0.79 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.79 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.79 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.79 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.60 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | PIM1 | P11309 | 1/20 | 0.56 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.56 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.56 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.56 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.56 |
| ▸ | NT5E | P21589 | 1/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.53 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23982227 | 1.00 | LMNA (0.79) | LMNATP53PNPHTTPDE4D | |
| SCHEMBL5983804 | 1.00 | LMNA (0.79) | LMNATP53PNPHTTPDE4D | |
| SCHEMBL6560256 | 1.00 | LMNA (0.79) | LMNATP53PNPHTTPDE4D | |
| SCHEMBL5983802 | 1.00 | LMNA (0.79) | LMNATP53PNPHTTPDE4D | |
| SCHEMBL6560259 | 1.00 | LMNA (0.79) | LMNATP53PNPHTTPDE4D | |
| SCHEMBL5983826 | 0.89 | PNP (0.67) | LMNATP53PNPHTTPDE4D | |
| SCHEMBL5064886 | 0.89 | PNP (0.78) | LMNATP53PNPHTTPDE4D | |
| SCHEMBL5983822 | 0.89 | PNP (0.67) | LMNATP53PNPHTTPDE4D | |
| SCHEMBL5064888 | 0.89 | PNP (0.78) | LMNATP53PNPHTTPDE4D | |
| SCHEMBL5983251 | 0.89 | PNP (0.78) | LMNATP53PNPHTTPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103788160-A | (2R,5R)-5-phosphoryl methoxy-2-(2-substituted adenine-9-yl)-2,5-dihydrofuran nucleoside analog as well as preparation method and application thereof | UNIV ZHENGZHOU | 2014-05-14 | — | — | CN | claimed |
| CN-103788160-B | (2R, 5R)-5-phosphatidyl methoxy-2-(2-substituted adenines-9-base)-2,5-dihydrofuran nucleoside analog and its production and use | 郑州大学 | 2016-07-06 | — | — | CN | disclosed |
| CN-103788160-A | (2R,5R)-5-phosphoryl methoxy-2-(2-substituted adenine-9-yl)-2,5-dihydrofuran nucleoside analog as well as preparation method and application thereof | UNIV ZHENGZHOU | 2014-05-14 | — | — | CN | disclosed |