Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 5/20 | 0.45 |
| ▸ | ESR1 | P03372 | 3/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | WEE1 | P30291 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PLEC | Q15149 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3420224 | 0.83 | MAOB (0.47) | PDK2ESR1ESR2MEN1KMT2A | |
| SCHEMBL2783173 | 0.78 | PDK2 (0.50) | PDK2ESR1ESR2MEN1KMT2A | |
| SCHEMBL9572301 | 0.76 | PDK2 (0.45) | PDK2ESR1ESR2CHEK1WEE1 | |
| SCHEMBL27392595 | 0.76 | PDK2 (0.65) | PDK2ESR1ESR2MEN1KMT2A | |
| SCHEMBL6292675 | 0.76 | PDK2 (0.65) | PDK2ESR1ESR2MEN1KMT2A | |
| SCHEMBL15845412 | 0.76 | PDK2 (0.65) | PDK2ESR1ESR2MEN1KMT2A | |
| SCHEMBL25434897 | 0.75 | ESR1 (0.44) | PDK2ESR1ESR2KMT2ATHRB | |
| SCHEMBL2688233 | 0.75 | ESR1 (0.59) | PDK2ESR1ESR2MEN1KMT2A | |
| SCHEMBL9572268 | 0.74 | PDK2 (0.43) | PDK2ESR1ESR2MEN1KMT2A | |
| SCHEMBL516147 | 0.74 | MAPT (0.58) | PDK2ESR1ESR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103965236-B | A kind of polycarbonate chainextender and preparation method thereof | NINGBO ZHETIE DAPHOON CHEMICAL Co.,Ltd. (CN) | 2015-08-26 | — | — | CN | claimed |
| CN-103965236-A | PC (polycarbonate)chain extender and preparation method thereof | NINGBO ZHETIE DAFENG CHEMICAL CO LTD | 2014-08-06 | — | — | CN | claimed |
| CN-103965236-B | A kind of polycarbonate chainextender and preparation method thereof | NINGBO ZHETIE DAPHOON CHEMICAL Co.,Ltd. (CN) | 2015-08-26 | — | — | CN | disclosed |
| CN-103965236-A | PC (polycarbonate)chain extender and preparation method thereof | NINGBO ZHETIE DAFENG CHEMICAL CO LTD | 2014-08-06 | — | — | CN | disclosed |