SCHEMBL27969799

SCHEMBL27969799

C/C=C/C(=O)On1cccc1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.31
GSTP1 P09211 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6050998 0.86 HCAR2 (0.34) HCAR2
SCHEMBL28097310 0.75 TDP1 (0.41)
SCHEMBL1216510 0.73 TSHR (0.38)
Pyridine SCHEMBL28161945 0.71 HCAR2 (0.37) HCAR2
SCHEMBL7901150 0.71
Furan SCHEMBL27880830 0.71 HCAR2 (0.37) HCAR2
SCHEMBL253593 0.69
SCHEMBL29186792 0.68 ALDH1A1 (0.32)
SCHEMBL27083013 0.68 GSTP1 (0.32) HCAR2GSTP1
SCHEMBL9047754 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103889978-A PROCESS FOR THE PREPARATION OF ISOXAZOLYL-METHOXY-NICOTINIC ACIDS HOFFMANN LA ROCHE 2014-06-25 CN disclosed