Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Pyridine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 10/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 10/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL28798151 | 0.98 | NAPRT (0.45) | NAPRTTSHRTDP1GRIN1GRIN2B | |
| Pyridine SCHEMBL4307620 | 0.98 | NAPRT (0.45) | NAPRTTSHRTDP1GRIN1GRIN2B | |
| Pyridine SCHEMBL28123986 | 0.95 | NAPRT (0.43) | NAPRTTSHRTDP1GRIN1GRIN2B | |
| Pyridine SCHEMBL27926369 | 0.95 | NAPRT (0.43) | NAPRTTSHRTDP1GRIN1GRIN2B | |
| Pyridine SCHEMBL27637980 | 0.95 | NAPRT (0.43) | NAPRTTSHRTDP1GRIN1GRIN2B | |
| Pyridine SCHEMBL27637981 | 0.95 | NAPRT (0.43) | NAPRTTSHRTDP1GRIN1GRIN2B | |
| Pyrazine SCHEMBL8097218 | 0.85 | CA2 (0.35) | NAPRTTSHRTDP1 | |
| Pyrimidine SCHEMBL3960330 | 0.83 | NAPRT (0.35) | NAPRTTSHRALDH1A1 | |
| Pyridine SCHEMBL6671998 | 0.82 | NAPRT (0.39) | NAPRTTSHRTDP1GRIN1GRIN2B | |
| Pyridine SCHEMBL7605509 | 0.82 | NAPRT (0.56) | NAPRTTSHRTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-209471106-U | A kind of portable water quality detector | 上海泰普克科技有限公司 | 2019-10-08 | — | — | CN | disclosed |
| CN-108444995-A | The field fast detection method of sulfur dioxide in a kind of wine | 上海应用技术大学 | 2018-08-24 | — | — | CN | disclosed |
| CN-206627464-U | The detection means of gas dew point | 中国神华能源股份有限公司 | 2017-11-10 | — | — | CN | disclosed |
| CN-103868078-B | A kind of liquid waste treating apparatus and process for treating waste liquor thereof | STATE GRID CORPORATION OF CHINA (CN) | 2016-02-03 | — | — | CN | disclosed |
| CN-203797671-U | Waste smoke treatment device | STATE GRID CORP CHINA | 2014-08-27 | — | — | CN | disclosed |
| CN-203797670-U | Liquid waste treatment device | STATE GRID CORP CHINA | 2014-08-27 | — | — | CN | disclosed |
| CN-103868078-A | Waste liquor treatment device and waste liquor treatment process | STATE GRID CORP CHINA | 2014-06-18 | — | — | CN | disclosed |