Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL700928 | 0.84 | IDO1 (0.50) | IDO1GAAALDH1A1SMN1; SMN2HPGD | |
| Hydrochloric Acid SCHEMBL709884 | 0.83 | IDO1 (0.49) | IDO1GAAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL28289668 | 0.83 | KCNA5 (0.51) | IDO1ALDH1A1HPGDHTTKCNA5 | |
| SCHEMBL20446470 | 0.78 | IDO1 (0.52) | IDO1GAAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL30079765 | 0.78 | IDO1 (0.52) | IDO1GAAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL23997640 | 0.78 | IDO1 (0.52) | IDO1GAAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL23979459 | 0.78 | ABL1 (0.48) | IDO1GAAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL21987982 | 0.77 | IDO1 (0.51) | IDO1GAAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL3007733 | 0.77 | IDO1 (0.51) | IDO1GAAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL16971616 | 0.77 | IDO1 (0.51) | IDO1GAAALDH1A1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101784516-B | Dipeptide analogs as coagulation factor inhibitors | BRISTOL MYERS SQUIBB CO | 2014-07-02 | — | — | CN | disclosed |