Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL709884 | 0.99 | IDO1 (0.49) | IDO1ALDH1A1GAAKDM4EGLA | |
| SCHEMBL21987982 | 0.85 | IDO1 (0.51) | IDO1ALDH1A1GAAKDM4EGLA | |
| SCHEMBL32665476 | 0.85 | NQO2 (0.48) | IDO1GAAKDM4EKCNA5KDM4A | |
| SCHEMBL711731 | 0.84 | IDO1 (0.50) | IDO1ALDH1A1GAAKDM4EGLA | |
| SCHEMBL4763233 | 0.84 | GRM2 (0.48) | IDO1KDM4EKCNA5KDM4AGRM2 | |
| SCHEMBL27970786 | 0.84 | IDO1 (0.46) | IDO1ALDH1A1GAAKDM4EGLA | |
| SCHEMBL23997640 | 0.83 | IDO1 (0.52) | IDO1ALDH1A1GAAKDM4EGLA | |
| SCHEMBL20446470 | 0.83 | IDO1 (0.52) | IDO1ALDH1A1GAAKDM4EGLA | |
| SCHEMBL30079765 | 0.83 | IDO1 (0.52) | IDO1ALDH1A1GAAKDM4EGLA | |
| SCHEMBL21987969 | 0.82 | IDO1 (0.48) | IDO1ALDH1A1GAAKDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124587-B2 | 2-(aminomethyl)-5-chlorobenzylamide derivatives and their use as inhibitors of the clotting factor Xa | THE MEDICINES COMPANY (LEIPZIG) GMBH (DE) | 2012-02-28 | — | — | US | disclosed |
| US-20090117185-A1 | 2-(Aminomethyl)-5-Chlorobenzylamide Derivatives and their use as Inhibitors of the Clotting Factor Xa | THE MEDICINES COMPANY (LEIPZIG) GMBH (DE) | 2009-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090117185-A1 | 2-(Aminomethyl)-5-Chlorobenzylamide Derivatives and their use as Inhibitors of the Clotting Factor Xa | F2, F11, TFPI | IDO1 1291/4885ALDH1A1 2053/4885GAA 764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.