Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 13/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2796190 | 0.99 | KCNH2 (0.45) | KCNH2SLC2A1MCHR1SMN1; SMN2 | |
| SCHEMBL12000108 | 0.88 | KCNH2 (0.53) | KCNH2SLC2A1 | |
| Hydrochloric Acid SCHEMBL2796081 | 0.87 | KCNH2 (0.53) | KCNH2SLC2A1 | |
| SCHEMBL13264459 | 0.86 | KCNH2 (0.50) | KCNH2SLC2A1 | |
| SCHEMBL2797361 | 0.86 | KCNH2 (0.47) | KCNH2SLC2A1MCHR1SMN1; SMN2 | |
| SCHEMBL2797153 | 0.85 | KCNH2 (0.47) | KCNH2SLC2A1MCHR1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2796093 | 0.85 | KCNH2 (0.46) | KCNH2SLC2A1MCHR1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2796186 | 0.85 | KCNH2 (0.46) | KCNH2SLC2A1MCHR1SMN1; SMN2 | |
| SCHEMBL12000206 | 0.84 | KDM4E (0.48) | KCNH2SLC2A1MCHR1SMN1; SMN2 | |
| SCHEMBL12000223 | 0.84 | KCNH2 (0.46) | KCNH2SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2204365-A1 | ALKYLSULFONE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2010-07-07 | — | — | EP | disclosed |
| US-20100168136-A1 | ALKYLSULFONE DERIVATIVES | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2010-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168136-A1 | ALKYLSULFONE DERIVATIVES | BACE1, APP, AMY1A | KCNH2 935/4885SLC2A1 2386/4885MCHR1 3108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.