Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 20/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27973726 | 0.92 | AGTR2 (0.44) | AGTR2CYP2C9CYP2B6 | |
| SCHEMBL1724215 | 0.90 | AGTR2 (0.52) | AGTR2CYP2C9CYP2B6 | |
| SCHEMBL4327781 | 0.87 | AGTR2 (0.45) | AGTR2CYP2C9CYP2B6 | |
| SCHEMBL4313287 | 0.87 | AGTR2 (0.48) | AGTR2CYP2C9CYP2B6 | |
| SCHEMBL4306715 | 0.87 | AGTR2 (0.43) | AGTR2CYP2C9CYP2B6 | |
| SCHEMBL4310758 | 0.87 | AGTR2 (0.49) | AGTR2CYP2C9CYP2B6 | |
| SCHEMBL1724924 | 0.81 | AGTR2 (0.54) | AGTR2CYP2C9CYP2B6 | |
| SCHEMBL1720369 | 0.78 | AGTR2 (0.69) | AGTR2CYP2C9CYP2B6 | |
| SCHEMBL27973544 | 0.78 | AGTR2 (0.62) | AGTR2 | |
| SCHEMBL28813223 | 0.76 | AGTR2 (0.39) | AGTR2CYP2C9CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101193886-B | New tricyclic angiotensin II agonists | VICORE PHARMA AB | 2014-08-27 | — | — | CN | disclosed |