Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | FYN | P06241 | 2/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17049238 | 0.86 | ALDH1A1 (0.59) | ALDH1A1TDP1CYP3A4TSHRHSD17B10 | |
| SCHEMBL28836921 | 0.79 | ALDH1A1 (0.51) | ALDH1A1CYP3A4GAADHFR | |
| SCHEMBL27975582 | 0.77 | ALDH1A1 (0.51) | ALDH1A1TDP1CYP3A4TSHRHSD17B10 | |
| SCHEMBL3788055 | 0.76 | ALDH1A1 (0.68) | ALDH1A1TDP1CYP3A4TSHRHSD17B10 | |
| SCHEMBL29685392 | 0.76 | KMT2A (0.50) | ALDH1A1CYP3A4TSHRHSD17B10MAPT | |
| SCHEMBL12844824 | 0.76 | KMT2A (0.50) | ALDH1A1CYP3A4TSHRHSD17B10MAPT | |
| SCHEMBL12492749 | 0.73 | ALDH1A1 (0.54) | ALDH1A1TDP1CYP3A4TSHRHSD17B10 | |
| SCHEMBL31607629 | 0.73 | ALDH1A1 (0.63) | ALDH1A1TDP1CYP3A4TSHRHSD17B10 | |
| SCHEMBL31661429 | 0.73 | ALDH1A1 (0.63) | ALDH1A1TDP1CYP3A4TSHRHSD17B10 | |
| SCHEMBL27186015 | 0.73 | ALDH1A1 (0.63) | ALDH1A1TDP1CYP3A4TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104114555-A | Pyrazolopyrimidine derivatives, process for their preparation and their therapeutic use | SANOFI SA | 2014-10-22 | — | — | CN | claimed |
| CN-104114555-A | Pyrazolopyrimidine derivatives, process for their preparation and their therapeutic use | SANOFI SA | 2014-10-22 | — | — | CN | disclosed |