Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27747728 | 0.82 | ALDH1A1 (0.37) | ALDH1A1HPGDTSHRNPC1RAB9A | |
| SCHEMBL27620736 | 0.80 | ALDH1A1 (0.35) | ALDH1A1HPGDTSHRNPC1RAB9A | |
| SCHEMBL27597829 | 0.80 | ALDH1A1 (0.35) | ALDH1A1HPGDTSHRNPC1RAB9A | |
| SCHEMBL27702946 | 0.80 | ALDH1A1 (0.35) | ALDH1A1HPGDTSHRNPC1RAB9A | |
| SCHEMBL2164754 | 0.68 | ALDH1A1 (0.41) | ALDH1A1HPGDTSHRNPC1RAB9A | |
| SCHEMBL28552569 | 0.67 | ALDH1A1 (0.39) | ALDH1A1HPGDNPC1RAB9AELANE | |
| SCHEMBL11227122 | 0.67 | ALDH1A1 (0.39) | ALDH1A1HPGDNPC1RAB9AELANE | |
| SCHEMBL29183161 | 0.66 | ALDH1A1 (0.38) | ALDH1A1HPGDNPC1RAB9AELANE | |
| SCHEMBL8624753 | 0.66 | ALDH1A1 (0.38) | ALDH1A1HPGDTSHRNPC1RAB9A | |
| SCHEMBL210845 | 0.66 | ALDH1A1 (0.38) | ALDH1A1HPGDTSHRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101203582-B | Ophthalmic devices comprising photochromic materials with extended pi-conjugated systems | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2015-08-19 | — | — | CN | disclosed |
| CN-104130768-A | Ophthalmic devices comprising photochromic materials having extended pi-conjugated systems | JOHNSON & JOHNSON VISION CARE | 2014-11-05 | — | — | CN | disclosed |
| CN-102667621-B | Photochromic material | TRANSITIONS OPTICAL INC | 2014-08-13 | — | — | CN | disclosed |