Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 6/20 | 0.48 |
| ▸ | GRIN2A | Q12879 | 6/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 5/20 | 0.48 |
| ▸ | GRIN3B | O60391 | 5/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.48 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.48 |
| ▸ | GRIN3A | Q8TCU5 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16997094 | 0.81 | GRIN1 (0.33) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL4751452 | 0.79 | GRIN1 (0.52) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL10415070 | 0.79 | TSHR (0.38) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL812216 | 0.79 | GRIN1 (0.68) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| Ammonia Solution, Strong SCHEMBL14695768 | 0.76 | GRIN1 (0.65) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL677103 | 0.75 | ALDH1A1 (0.32) | MEN1KMT2A | |
| SCHEMBL3162219 | 0.74 | GRIN1 (0.42) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL7423338 | 0.74 | GRIN1 (0.42) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL4807168 | 0.74 | GRIN1 (0.42) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL5608473 | 0.73 | MEN1 (0.41) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104583337-A | Coloring compound, ink containing the coloring compound, resist composition for color filter, and ink sheet for thermal transfer recording | CANON KK | 2015-04-29 | — | — | CN | disclosed |
| CN-103987711-A | 8-carbamoyl-2- (2, 3-disubstituted pyridin-6-yl) -1,2,3, 4-tetrahydroisoquinoline derivatives as apoptosis inducers for the treatment of cancer and immune and autoimmune diseases | ABBVIE INC | 2014-08-13 | — | — | CN | disclosed |