SCHEMBL27977904

SCHEMBL27977904

NC(=O)C1C2CCCC1C2

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 3/20 0.34
HRH3 Q9Y5N1 1/20 0.33
KDM4E B2RXH2 1/20 0.32
MAPT P10636 1/20 0.32
KMT2A Q03164 1/20 0.32
ATM Q13315 1/20 0.32
CYP2D6 P10635 1/20 0.32
ALOX5 P09917 1/20 0.32
GLI1 P08151 1/20 0.32
PARP10 Q53GL7 1/20 0.31
NOS2 P35228 1/20 0.31
GRM2 Q14416 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3629197 0.86 EPHX1 (0.36) EPHX1HRH3KDM4EMAPTKMT2A
SCHEMBL2549796 0.83 LMNA (0.33) EPHX1KDM4EMAPTKMT2AATM
SCHEMBL15232945 0.83 GLI1 (0.32) GLI1
SCHEMBL29950626 0.76 POLB (0.40) KDM4EMAPTKMT2AGRM2
SCHEMBL22660589 0.76 POLB (0.40) KDM4EMAPTKMT2AGRM2
SCHEMBL24516573 0.75 MEN1 (0.37) KMT2ACYP2D6
SCHEMBL3774101 0.75 MEN1 (0.37) KMT2ACYP2D6
SCHEMBL8795414 0.75 LMNA (0.44) KDM4EMAPTKMT2A
SCHEMBL6078824 0.75 MEN1 (0.37) KMT2ACYP2D6
SCHEMBL3764733 0.75 MEN1 (0.37) KMT2ACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4695231-A1 COMPOUNDS, COMPOSITIONS, AND METHODS Tenvie Therapeutics Inc. (US) 2026-02-18 EP disclosed
WO-2024216209-A1 COMPOUNDS, COMPOSITIONS, AND METHODS NICO THERAPEUTICS, INC. (US) 2024-10-17 WO disclosed
CN-103958473-A Amide compound, composition and application thereof ADVINUS THERAPEUTICS LTD 2014-07-30 CN disclosed