SCHEMBL27978098

SCHEMBL27978098

Cc1noc(C)c1Cn1cc(-n2c(=O)n(C)n(C(=O)O)c2=O)cn1

nearest known ligand 0.79

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ TAS2R8 Q9NYW2 20/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1279357 0.89 TAS2R8 (1.00) TAS2R8
SCHEMBL1279009 0.89 TAS2R8 (0.74) TAS2R8
SCHEMBL17480028 0.87 TAS2R8 (0.72) TAS2R8
SCHEMBL1279587 0.81 TAS2R8 (1.00) TAS2R8
SCHEMBL1278900 0.77 TAS2R8 (1.00) TAS2R8
SCHEMBL1279140 0.77 TAS2R8 (1.00) TAS2R8
SCHEMBL1279575 0.77 TAS2R8 (0.77) TAS2R8
SCHEMBL1279701 0.77 TAS2R8 (0.73) TAS2R8
SCHEMBL18351071 0.77 TAS2R8 (0.86) TAS2R8
SCHEMBL1279175 0.75 TAS2R8 (1.00) TAS2R8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104130247-A Human T2R bitter taste receptors and the use thereof SENOMYX INC 2014-11-05 — — CN disclosed
CN-101828111-B Human T2R bitter taste receptor and uses thereof SENOMYX INC 2014-07-23 — — CN disclosed
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