Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 20/20 | 0.76 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.62 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.61 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27979174 | 0.88 | PIK3CD (0.67) | PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL2674915 | 0.87 | PIK3CD (1.00) | PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL2675330 | 0.86 | PIK3CD (0.81) | PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL2674043 | 0.86 | PIK3CD (0.81) | PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL2675049 | 0.86 | PIK3CD (0.81) | PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL3719427 | 0.85 | PIK3CD (0.78) | PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL2673552 | 0.84 | PIK3CD (0.80) | PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL2674290 | 0.84 | PIK3CD (0.74) | PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL2673442 | 0.84 | PIK3CD (0.94) | PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL2674547 | 0.84 | PIK3CD (0.79) | PIK3CDPIK3CBPIK3CGPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102459272-B | Bicyclic pyrimidine PI3K inhibitor compounds selective for P110 delta, and methods of use | GENENTECH INC | 2014-08-06 | — | — | CN | disclosed |