Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 20/20 | 0.67 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.67 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.61 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27979008 | 0.88 | PIK3CD (0.76) | PIK3CDPIK3CBPIK3CAPIK3CG | |
| SCHEMBL2673859 | 0.88 | PIK3CD (0.86) | PIK3CDPIK3CBPIK3CAPIK3CG | |
| SCHEMBL2674017 | 0.88 | PIK3CD (0.69) | PIK3CDPIK3CBPIK3CAPIK3CG | |
| SCHEMBL2674356 | 0.85 | PIK3CD (0.84) | PIK3CDPIK3CBPIK3CAPIK3CG | |
| SCHEMBL2675001 | 0.84 | PIK3CD (0.74) | PIK3CDPIK3CBPIK3CAPIK3CG | |
| SCHEMBL2674471 | 0.83 | PIK3CD (0.57) | PIK3CDPIK3CBPIK3CAPIK3CG | |
| SCHEMBL28813760 | 0.83 | PIK3CD (0.81) | PIK3CDPIK3CBPIK3CAPIK3CG | |
| SCHEMBL2673912 | 0.82 | PIK3CD (0.89) | PIK3CDPIK3CBPIK3CAPIK3CG | |
| SCHEMBL2674853 | 0.81 | PIK3CD (0.88) | PIK3CDPIK3CBPIK3CAPIK3CG | |
| SCHEMBL27979137 | 0.81 | PIK3CD (0.70) | PIK3CDPIK3CBPIK3CAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102459272-B | Bicyclic pyrimidine PI3K inhibitor compounds selective for P110 delta, and methods of use | GENENTECH INC | 2014-08-06 | — | — | CN | disclosed |