Phenacyl Chloride

Phenacyl Chloride

SCHEMBL27980271

CCN.O=C(CCl)c1ccccc1

nearest known ligand 0.79

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 3/20 0.79
ALDH1A1 P00352 3/20 0.79
MAPK1 P28482 2/20 0.79
HIF1A Q16665 2/20 0.79
TRPA1 O75762 1/20 0.79
MAPT P10636 4/20 0.52
KMT2A Q03164 4/20 0.52
MEN1 O00255 3/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
CES1 P23141 2/20 0.52
KDM4E B2RXH2 1/20 0.52
CYP3A4 P08684 1/20 0.52
HPGD P15428 1/20 0.52
ALOX15 P16050 1/20 0.52
PTPN1 P18031 2/20 0.48
THRA P10827 1/20 0.47
THRB P10828 1/20 0.47
TP53 P04637 1/20 0.47
L3MBTL1 Q9Y468 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenacyl Chloride SCHEMBL2314766 0.89 ALDH1A1 (1.00) GSK3BALDH1A1MAPK1HIF1ATRPA1
Phenacyl Chloride SCHEMBL55444 0.89 ALDH1A1 (1.00) GSK3BALDH1A1MAPK1HIF1ATRPA1
Phenacyl Chloride SCHEMBL4787265 0.87 ALDH1A1 (0.86) GSK3BALDH1A1MAPK1HIF1ATRPA1
Phenacyl Chloride SCHEMBL5139857 0.87 ALDH1A1 (0.95) GSK3BALDH1A1MAPK1HIF1ATRPA1
Phenacyl Chloride SCHEMBL28256528 0.87 ALDH1A1 (0.95) GSK3BALDH1A1MAPK1HIF1ATRPA1
Phenacyl Chloride SCHEMBL14715802 0.87 ALDH1A1 (0.95) GSK3BALDH1A1MAPK1HIF1ATRPA1
Phenacyl Chloride SCHEMBL27611889 0.87 ALDH1A1 (0.95) GSK3BALDH1A1MAPK1HIF1ATRPA1
Phenacyl Chloride SCHEMBL28034037 0.87 ALDH1A1 (0.95) GSK3BALDH1A1MAPK1HIF1ATRPA1
Phenacyl Chloride SCHEMBL7068908 0.85 GSK3B (0.83) GSK3BALDH1A1MAPK1HIF1ATRPA1
Phenacyl Chloride SCHEMBL9451036 0.85 ALDH1A1 (0.83) GSK3BALDH1A1MAPK1HIF1ATRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104080729-A Mmp-targeted therapeutic and/or diagnostic nanocarriers MALLINCKRODT INC 2014-10-01 CN disclosed