SCHEMBL2798087

SCHEMBL2798087

O=c1ccc2c(OCCc3ccccc3)c3ccoc3cc2o1

nearest known ligand 0.86

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNA3 P22001 20/20 0.86
KCNA5 P22460 16/20 0.86
KDM4E B2RXH2 1/20 0.86
ALDH1A1 P00352 1/20 0.86
LMNA P02545 1/20 0.86
CYP1A2 P05177 1/20 0.86
CYP3A4 P08684 1/20 0.86
CYP2D6 P10635 1/20 0.86
CYP2C9 P11712 1/20 0.86
TSHR P16473 1/20 0.86
NFKB1 P19838 1/20 0.86
MAPK1 P28482 1/20 0.86
CYP2C19 P33261 1/20 0.86
BLM P54132 1/20 0.86
PMP22 Q01453 1/20 0.86
HIF1A Q16665 1/20 0.86
NPSR1 Q6W5P4 1/20 0.86
HSD17B10 Q99714 1/20 0.86
KCNA1 Q09470 3/20 0.77
KCNA4 P22459 2/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2801814 0.94 KCNA3 (0.93) KCNA3KCNA5KDM4EALDH1A1LMNA
SCHEMBL29386652 0.93 KCNA3 (1.00) KCNA3KCNA5KDM4EALDH1A1LMNA
SCHEMBL2801777 0.93 KCNA3 (1.00) KCNA3KCNA5KDM4EALDH1A1LMNA
SCHEMBL2802485 0.92 KCNA3 (0.98) KCNA3KCNA5KDM4EALDH1A1LMNA
SCHEMBL2800519 0.87 KCNA3 (0.80) KCNA3KCNA5KDM4EALDH1A1LMNA
SCHEMBL2581120 0.87 KCNA3 (1.00) KCNA3KCNA5KDM4EALDH1A1LMNA
SCHEMBL2586220 0.86 KCNA3 (1.00) KCNA3KCNA5KDM4EALDH1A1LMNA
SCHEMBL2579687 0.86 KCNA3 (1.00) KCNA3KCNA5KDM4EALDH1A1LMNA
SCHEMBL2583446 0.85 KCNA3 (1.00) KCNA3KCNA5KDM4EALDH1A1LMNA
SCHEMBL29410610 0.85 KCNA3 (1.00) KCNA3KCNA5KDM4EALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7772408-B1 Substituted 5-alkoxypsoralens as inhibitors of potassium channel activity in lymphocytes and other cells THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-08-10 US claimed
WO-2025082731-A1 INTRANASAL FORMULATIONS FOR TREATING OBSTRUCTIVE SLEEP APNEA MOSANNA THERAPEUTICS AG (CH) 2025-04-24 WO disclosed
US-7772408-B1 Substituted 5-alkoxypsoralens as inhibitors of potassium channel activity in lymphocytes and other cells THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-08-10 US disclosed
US-7772408-B1 Substituted 5-alkoxypsoralens as inhibitors of potassium channel activity in lymphocytes and other cells THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-08-10 US disclosed
US-7772408-B1 Substituted 5-alkoxypsoralens as inhibitors of potassium channel activity in lymphocytes and other cells THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-08-10 US disclosed