SCHEMBL2802485

SCHEMBL2802485

O=c1ccc2c(OCCCCCc3ccccc3)c3ccoc3cc2o1

nearest known ligand 0.98

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNA3 P22001 20/20 0.98
KCNA5 P22460 14/20 0.98
KDM4E B2RXH2 1/20 0.98
ALDH1A1 P00352 1/20 0.98
LMNA P02545 1/20 0.98
CYP1A2 P05177 1/20 0.98
CYP3A4 P08684 1/20 0.98
CYP2D6 P10635 1/20 0.98
CYP2C9 P11712 1/20 0.98
TSHR P16473 1/20 0.98
NFKB1 P19838 1/20 0.98
MAPK1 P28482 1/20 0.98
CYP2C19 P33261 1/20 0.98
BLM P54132 1/20 0.98
PMP22 Q01453 1/20 0.98
HIF1A Q16665 1/20 0.98
NPSR1 Q6W5P4 1/20 0.98
HSD17B10 Q99714 1/20 0.98
KCNA1 Q09470 3/20 0.77
KCNA4 P22459 2/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29386652 0.99 KCNA3 (1.00) KCNA3KCNA5KDM4EALDH1A1LMNA
SCHEMBL2801777 0.99 KCNA3 (1.00) KCNA3KCNA5KDM4EALDH1A1LMNA
SCHEMBL2801814 0.95 KCNA3 (0.93) KCNA3KCNA5KDM4EALDH1A1LMNA
SCHEMBL2798087 0.92 KCNA3 (0.86) KCNA3KCNA5KDM4EALDH1A1LMNA
SCHEMBL2585444 0.88 KCNA3 (1.00) KCNA3KCNA5KDM4EALDH1A1LMNA
SCHEMBL2579687 0.87 KCNA3 (1.00) KCNA3KCNA5KDM4EALDH1A1LMNA
SCHEMBL29410610 0.87 KCNA3 (1.00) KCNA3KCNA5KDM4EALDH1A1LMNA
SCHEMBL2585454 0.87 KCNA3 (1.00) KCNA3KCNA5KDM4EALDH1A1LMNA
SCHEMBL2586220 0.85 KCNA3 (1.00) KCNA3KCNA5KDM4EALDH1A1LMNA
SCHEMBL2583446 0.84 KCNA3 (1.00) KCNA3KCNA5KDM4EALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210393857-A1 SMALL MOLECULE DRUGS AND METHODS TO ACCELERATE OSSEOINTEGRATION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-12-23 US claimed
EP-3876871-A1 SMALL MOLECULE DRUGS AND METHODS TO ACCELERATE OSSEOINTEGRATION The Regents of the University of California (US) 2021-09-15 EP claimed
US-7772408-B1 Substituted 5-alkoxypsoralens as inhibitors of potassium channel activity in lymphocytes and other cells THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-08-10 US claimed
WO-2025082731-A1 INTRANASAL FORMULATIONS FOR TREATING OBSTRUCTIVE SLEEP APNEA MOSANNA THERAPEUTICS AG (CH) 2025-04-24 WO disclosed
US-20210393857-A1 SMALL MOLECULE DRUGS AND METHODS TO ACCELERATE OSSEOINTEGRATION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-12-23 US disclosed
US-20210393857-A1 SMALL MOLECULE DRUGS AND METHODS TO ACCELERATE OSSEOINTEGRATION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-12-23 US disclosed
EP-3876871-A1 SMALL MOLECULE DRUGS AND METHODS TO ACCELERATE OSSEOINTEGRATION The Regents of the University of California (US) 2021-09-15 EP disclosed
US-7772408-B1 Substituted 5-alkoxypsoralens as inhibitors of potassium channel activity in lymphocytes and other cells THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-08-10 US disclosed
US-7772408-B1 Substituted 5-alkoxypsoralens as inhibitors of potassium channel activity in lymphocytes and other cells THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-08-10 US disclosed
US-7772408-B1 Substituted 5-alkoxypsoralens as inhibitors of potassium channel activity in lymphocytes and other cells THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210393857-A1 SMALL MOLECULE DRUGS AND METHODS TO ACCELERATE OSSEOINTEGRATION PER2, NCOR2, NR4A2 KCNA3 3196/4885KCNA5 3370/4885KDM4E 1437/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.