Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.36 |
| ▸ | P4HB | P07237 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10617353 | 0.82 | TSHR (0.55) | TSHRPOLBMAPK1GABRA1GABRB2 | |
| SCHEMBL30455902 | 0.80 | TSHR (0.64) | TSHRPOLBMAPK1GABRA1GABRB2 | |
| SCHEMBL188373 | 0.80 | TSHR (0.64) | TSHRPOLBMAPK1GABRA1GABRB2 | |
| SCHEMBL1952938 | 0.79 | TSHR (0.53) | TSHRPOLBMAPK1GABRA1GABRB2 | |
| SCHEMBL1954270 | 0.76 | TSHR (0.50) | TSHRPOLBMAPK1GABRA1GABRB2 | |
| SCHEMBL1954000 | 0.76 | TSHR (0.48) | TSHRPOLBMAPK1GABRA1GABRB2 | |
| SCHEMBL1778574 | 0.76 | TSHR (0.48) | TSHRPOLBMAPK1GABRA1GABRB2 | |
| SCHEMBL27833226 | 0.75 | POLB (0.37) | TSHRPOLBMAPK1HTR1AHSPA5 | |
| SCHEMBL27950263 | 0.74 | TSHR (0.47) | TSHRPOLBMAPK1GABRA1GABRB2 | |
| SCHEMBL1954008 | 0.74 | TSHR (0.47) | TSHRPOLBMAPK1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102471244-B | Process for producing N-substituted carbamate, process for producing isocyanate using the N-substituted carbamate, and composition for transporting and storing N-substituted carbamate containing N-substituted carbamate and aromatic hydroxy compound | ASAHI CHEMICAL CORP | 2014-09-24 | — | — | CN | disclosed |