Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.79 |
| ▸ | AURKA | O14965 | 2/20 | 0.79 |
| ▸ | JAK2 | O60674 | 2/20 | 0.79 |
| ▸ | LCK | P06239 | 2/20 | 0.79 |
| ▸ | LYN | P07948 | 2/20 | 0.79 |
| ▸ | KIT | P10721 | 2/20 | 0.79 |
| ▸ | TYK2 | P29597 | 2/20 | 0.79 |
| ▸ | TEC | P42680 | 2/20 | 0.79 |
| ▸ | TXK | P42681 | 2/20 | 0.79 |
| ▸ | BMX | P51813 | 2/20 | 0.79 |
| ▸ | ITK | Q08881 | 2/20 | 0.79 |
| ▸ | CDK2 | P24941 | 1/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27982680 | 0.95 | BTK (0.77) | BTKAURKAJAK2LCKLYN | |
| SCHEMBL123056 | 0.88 | BTK (1.00) | BTKAURKAJAK2LCKLYN | |
| SCHEMBL123345 | 0.83 | BTK (0.80) | BTKAURKAJAK2LCKLYN | |
| SCHEMBL27982632 | 0.82 | BTK (1.00) | BTKAURKAJAK2LCKLYN | |
| SCHEMBL27982053 | 0.81 | BTK (1.00) | BTKAURKAJAK2LCKLYN | |
| SCHEMBL27982614 | 0.81 | BTK (0.77) | BTKAURKAJAK2LCKLYN | |
| SCHEMBL27982111 | 0.80 | BTK (1.00) | BTKAURKAJAK2LCKLYN | |
| SCHEMBL27982586 | 0.80 | BTK (1.00) | BTKAURKAJAK2LCKLYN | |
| SCHEMBL27982122 | 0.80 | BTK (1.00) | BTKAURKAJAK2LCKLYN | |
| SCHEMBL27982674 | 0.79 | BTK (1.00) | BTKAURKAJAK2LCKLYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102325753-B | Carbazole carboxamide compounds useful as kinase inhibitors | BRISTOL MYERS SQUIBB CO | 2014-09-10 | — | — | CN | claimed |