SCHEMBL27984697

SCHEMBL27984697

Cc1cc(Cc2cc(CN)cc(C(C)(C)C)c2OC(=O)c2ccc(C(=O)Oc3c(Cc4cc(C)cc(C(C)(C)C)c4O)cc(CN)cc3C(C)(C)C)cc2)c(O)c(C(C)(C)C)c1

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 2/20 0.51
CYP2C9 P11712 2/20 0.50
CYP2C19 P33261 2/20 0.50
HIF1A Q16665 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
CYP2D6 P10635 1/20 0.46
HSD17B10 Q99714 1/20 0.46
NR1H4 Q96RI1 2/20 0.37
ALDH1A1 P00352 1/20 0.35
CA2 P00918 1/20 0.35
POLB P06746 1/20 0.35
TYR P14679 1/20 0.35
LOXL2 Q9Y4K0 1/20 0.34
F2 P00734 1/20 0.33
PRSS1 P07477 1/20 0.33
PRSS2 P07478 1/20 0.33
PRSS3 P35030 1/20 0.33
VCAM1 P19320 1/20 0.32
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL97424 0.91 HSPA5 (0.61) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL29349870 0.91 HSPA5 (0.61) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL29381652 0.91 HSPA5 (0.61) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL328984 0.87 HSPA5 (0.56) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL30612523 0.87 HSPA5 (0.56) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL10783426 0.85 HSPA5 (0.57) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL9396120 0.83 HSPA5 (0.57) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL9578179 0.80 CYP2C9 (0.48) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL4369586 0.78 HSPA5 (0.67) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL17171702 0.78 HSPA5 (0.41) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105693698-B Multi-functional hindered amine light stabilizer 巴斯夫欧洲公司 2019-11-22 CN disclosed
CN-110446749-A Light stabilizer mixture BASF SE 2019-11-12 CN disclosed
CN-106459255-B Oxygen-containing imide copolymer or high molecular polymer as flame retardant for plastic material 弗劳恩霍夫应用研究促进协会 2019-11-05 CN disclosed
CN-104520351-B Polyetherimide compositions, manufacturing method and the product formed by it 沙特基础全球技术有限公司 2019-09-27 CN disclosed
CN-110023455-A The liquid crystal film of polymerisable liquid crystal material and polymerization 默克专利股份有限公司 2019-07-16 CN disclosed
CN-110023456-A Polymerizable LC medium and the polymer film with planar wave dispersion 默克专利股份有限公司 2019-07-16 CN disclosed
CN-106332548-B Polyurethane scorch inhibitor 范德比尔特化学品有限责任公司 2019-06-14 CN disclosed
CN-109790465-A The liquid crystal film of polymerisable liquid crystal material and polymerization 默克专利股份有限公司 2019-05-21 CN disclosed
CN-105960432-B Phosphorus-containing 3-phenylbenzofuran-2-one derivatives as stabilizers 巴斯夫欧洲公司 2019-02-15 CN disclosed
CN-105531300-B Polyetherimides, methods of manufacture, and articles formed therefrom 沙特基础全球技术有限公司 2018-06-22 CN disclosed
CN-106332548-A Polyurethane scorch inhibitor 范德比尔特化学品有限责任公司 2017-01-11 CN disclosed
CN-105555764-A Polyetherimides, methods of manufacture, and articles formed therefrom SABIC INNOVATIVE PLASTICS IP BV 2016-05-04 CN disclosed
CN-105531300-A Polyetherimides, methods of manufacture, and articles formed therefrom SABIC INNOVATIVE PLASTICS IP BV 2016-04-27 CN disclosed
CN-104640961-A Polymers for lubricant compositions and methods of forming the same BASF SE 2015-05-20 CN disclosed
CN-104039879-A Organic semiconductor device and manufacturing method thereof BASF SE 2014-09-10 CN disclosed