SCHEMBL4369586

SCHEMBL4369586

CC(=O)Oc1c(Cc2cc(C)cc(C(C)(C)C)c2O)cc(C)cc1C(C)(C)C

nearest known ligand 0.67

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 2/20 0.67
CYP2C9 P11712 2/20 0.65
CYP2C19 P33261 2/20 0.65
HIF1A Q16665 2/20 0.65
SMN1; SMN2 Q16637 2/20 0.65
CYP2D6 P10635 1/20 0.58
HSD17B10 Q99714 1/20 0.58
ALDH1A1 P00352 1/20 0.46
CA2 P00918 1/20 0.46
POLB P06746 1/20 0.46
TYR P14679 1/20 0.46
VCAM1 P19320 5/20 0.39
GLRA3 O75311 1/20 0.38
GLRB P48167 1/20 0.38
AMY1A P0DUB6 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15980586 0.93 HSPA5 (0.53) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL29407804 0.87 HSPA5 (0.60) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL499728 0.87 HSPA5 (0.60) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL28395857 0.86 HSPA5 (0.63) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL27785927 0.86 HSPA5 (0.46) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL29381652 0.85 HSPA5 (0.61) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL29349870 0.85 HSPA5 (0.61) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL97424 0.85 HSPA5 (0.61) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL29362485 0.84 HSPA5 (0.60) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL35108 0.84 HSPA5 (0.60) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0897133-B1 Image dye-forming couplers and photographic elements containing them EASTMAN KODAK CO (US) 2004-07-14 EP claimed
US-6071683-A PHOTOSTABILITY EASTMAN KODAK COMPANY (US) 2000-06-06 US claimed
EP-0897133-A1 Image dye-forming couplers and photographic elements containing them EASTMAN KODAK COMPANY (US) 1999-02-17 EP claimed
US-20220119624-A1 METHOD OF STABILIZING HALOGEN-FREE THERMOPLASTIC RECYCLATES, PLASTICS COMPOSITION, STABILIZER COMPOSITION AND USE OF THE STABILIZER COMPOSITION Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e. V. (DE) 2022-04-21 US disclosed
EP-3354709-B1 COMPOUNDS AND LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2019-09-25 EP disclosed
EP-3354709-A1 COMPOUNDS AND LIQUID CRYSTALLINE MEDIUM Merck Patent GmbH (DE) 2018-08-01 EP disclosed
US-8637228-B1 Color photographic silver halide paper and use KODAK ALARIS INC. (US) 2014-01-28 US disclosed
US-8637228-B1 Color photographic silver halide paper and use KODAK ALARIS INC. (US) 2014-01-28 US disclosed
US-8546070-B1 Color photographic silver halide paper and use EASTMAN KODAK COMPANY (US) 2013-10-01 US disclosed
US-8546070-B1 Color photographic silver halide paper and use EASTMAN KODAK COMPANY (US) 2013-10-01 US disclosed
EP-1816001-B1 INK-JET RECORDING MEDIUM AND METHOD FOR PRODUCTION THEREOF CANON KK (JP) 2012-06-13 EP disclosed
US-20060188671-A1 Article, ink recording medium, ink-jet recording medium and production process thereof CANON KABUSHIKI KAISHA (JP) 2006-08-24 US disclosed
EP-1329767-A2 Direct view photographic element containing a particular green record EASTMAN KODAK COMPANY (US) 2003-07-23 EP disclosed
EP-1329766-A1 Direct view photographic element containing a specific red recording layer unit EASTMAN KODAK COMPANY (US) 2003-07-23 EP disclosed
US-6558886-B1 Contains a coupler or couplers that provide an improved flesh tone reproduction EASTMAN KODAK COMPANY 2003-05-06 US disclosed
US-6555304-B1 A red light sensitized silver halide emulsion comprising a cyan dye-forming narrow bandwidth coupler, and a second coupler selected from a magenta and a cyan dye-forming coupler; improved flesh tone reproduction and photostability EASTMAN KODAK COMPANY 2003-04-29 US disclosed
US-5681689-A COUPLING WITH OXIDIZED COLOR DEVELOPER EASTMAN KODAK COMPANY (US) 1997-10-28 US disclosed
EP-0144477-B1 METHOD FOR PRODUCING BISPHENOL DERIVATIVES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-03-18 EP disclosed
US-4562281-A Production of bisphenol derivatives SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-12-31 US disclosed
EP-0144477-A1 Method for producing bisphenol derivatives SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-06-19 EP disclosed