SCHEMBL27985278

SCHEMBL27985278

Cc1cn(-c2ccc(-n3cnc(C)c3)cc2)cn1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.65
CYP3A4 P08684 1/20 0.65
CYP2D6 P10635 1/20 0.65
CYP19A1 P11511 1/20 0.65
CYP2C9 P11712 1/20 0.65
CYP2C19 P33261 1/20 0.65
CYP2E1 P05181 1/20 0.60
CYP2A6 P11509 1/20 0.60
PDE4A P27815 1/20 0.53
PDE4B Q07343 1/20 0.53
PDE4C Q08493 1/20 0.53
PDE4D Q08499 1/20 0.53
MAOA P21397 4/20 0.47
MAOB P27338 4/20 0.47
NR2E1 Q9Y466 2/20 0.47
PDE3B Q13370 1/20 0.41
PDE3A Q14432 1/20 0.41
PTK2 Q05397 1/20 0.41
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4666728 0.89 CYP3A4 (0.56) CYP1A2CYP3A4CYP2D6CYP19A1CYP2C9
SCHEMBL19272800 0.89 CYP1A2 (0.56) CYP1A2CYP3A4CYP2D6CYP19A1CYP2C9
SCHEMBL4668245 0.89 CYP1A2 (0.56) CYP1A2CYP3A4CYP2D6CYP19A1CYP2C9
SCHEMBL12988609 0.89 CYP3A4 (0.56) CYP1A2CYP3A4CYP2D6CYP19A1CYP2C9
SCHEMBL2283022 0.89 CYP2E1 (0.65) CYP1A2CYP3A4CYP2D6CYP19A1CYP2C9
Hydrochloric Acid SCHEMBL21412170 0.88 CYP3A4 (0.54) CYP1A2CYP3A4CYP2D6CYP19A1CYP2C9
SCHEMBL22199024 0.87 CYP2E1 (0.62) CYP1A2CYP3A4CYP2D6CYP19A1CYP2C9
SCHEMBL14704038 0.86 CYP1A2 (0.66) CYP1A2CYP3A4CYP2D6CYP19A1CYP2C9
SCHEMBL270618 0.86 CYP1A2 (0.53) CYP1A2CYP3A4CYP2D6CYP19A1CYP2C9
SCHEMBL10280811 0.86 CYP1A2 (0.61) CYP1A2CYP3A4CYP2D6CYP19A1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104031076-B A kind of two imidazoles nitrogen ligand regulation and control 1,3,5-trimesic acid Zn complex and preparation method thereof HENGYANG NORMAL UNIVERSITY (CN) 2016-01-06 CN claimed
CN-104031076-A Diimidazole nitrogen ligand-controlled 1,3,5-trimesic acid zinc complex and preparation method thereof UNIV HENGYANG NORMAL 2014-09-10 CN claimed
CN-104031076-B A kind of two imidazoles nitrogen ligand regulation and control 1,3,5-trimesic acid Zn complex and preparation method thereof HENGYANG NORMAL UNIVERSITY (CN) 2016-01-06 CN disclosed
CN-104031076-A Diimidazole nitrogen ligand-controlled 1,3,5-trimesic acid zinc complex and preparation method thereof UNIV HENGYANG NORMAL 2014-09-10 CN disclosed
CN-104031076-A Diimidazole nitrogen ligand-controlled 1,3,5-trimesic acid zinc complex and preparation method thereof UNIV HENGYANG NORMAL 2014-09-10 CN disclosed