SCHEMBL27985331

SCHEMBL27985331

Brc1cccc(C#Cc2ccccc2)c1Br

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.50
ALDH1A1 P00352 4/20 0.50
MAPT P10636 3/20 0.50
MEN1 O00255 3/20 0.50
CYP1A2 P05177 3/20 0.50
CYP3A4 P08684 3/20 0.50
CYP2C9 P11712 3/20 0.50
HPGD P15428 3/20 0.50
CYP2C19 P33261 3/20 0.50
KMT2A Q03164 3/20 0.50
KDM4E B2RXH2 3/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
HSD17B10 Q99714 2/20 0.50
APP P05067 1/20 0.50
CA12 O43570 5/20 0.47
CA2 P00918 5/20 0.47
CA9 Q16790 5/20 0.47
FFAR1 O14842 1/20 0.45
RAB9A P51151 3/20 0.43
DHFR P00374 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29843195 0.85 FFAR1 (0.57) NPC1ALDH1A1MAPTMEN1CYP1A2
SCHEMBL1920588 0.85 FFAR1 (0.57) NPC1ALDH1A1MAPTMEN1CYP1A2
SCHEMBL28752319 0.83 FFAR1 (0.56) NPC1ALDH1A1MAPTMEN1CYP1A2
SCHEMBL12408477 0.78 FFAR1 (0.59) NPC1ALDH1A1MAPTMEN1CYP1A2
SCHEMBL5871989 0.77 APP (0.75) NPC1ALDH1A1MAPTMEN1CYP1A2
SCHEMBL2114742 0.77 APP (0.75) NPC1ALDH1A1MAPTMEN1CYP1A2
SCHEMBL10623230 0.76 APP (0.57) NPC1ALDH1A1MAPTMEN1CYP1A2
SCHEMBL13299908 0.74 APP (0.55) NPC1ALDH1A1MAPTMEN1CYP1A2
SCHEMBL14882953 0.73 FFAR1 (0.51) NPC1ALDH1A1MAPTMEN1CYP1A2
SCHEMBL3797526 0.73 APP (0.60) NPC1ALDH1A1MAPTMEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104080758-A Graphene nanoribbon precursors and monomers suitable for making the same BASF SE 2014-10-01 CN disclosed