Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.75 |
| ▸ | NPC1 | O15118 | 4/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | HPGD | P15428 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | GRM5 | P41594 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2114742 | 1.00 | APP (0.75) | APPNPC1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10437173 | 0.87 | APP (0.57) | APPNPC1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL2747094 | 0.87 | APP (0.57) | APPNPC1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL15009036 | 0.87 | APP (0.57) | APPNPC1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4844706 | 0.87 | APP (0.57) | APPNPC1CYP1A2CYP3A4CYP2C9 | |
| Diphenylacetylene SCHEMBL29188592 | 0.87 | APP (1.00) | APPNPC1CYP1A2CYP3A4CYP2C9 | |
| Diphenylacetylene SCHEMBL960609 | 0.87 | APP (1.00) | APPNPC1CYP1A2CYP3A4CYP2C9 | |
| Diphenylacetylene SCHEMBL68254 | 0.87 | APP (1.00) | APPNPC1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1666085 | 0.86 | APP (0.63) | APPNPC1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL28752319 | 0.85 | FFAR1 (0.56) | APPNPC1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049386-B2 | Compositions and methods for thermosetting molecules in organic compositions | HONEYWELL INTERNATIONAL INC. (US) | 2006-05-23 | — | — | US | disclosed |
| EP-1309639-A4 | COMPOSITIONS AND METHODS FOR THERMOSETTING MOLECULES IN ORGANIC COMPOSITIONS | HONEYWELL INT INC (US) | 2004-12-08 | — | — | EP | disclosed |
| US-6803441-B2 | INCORPORATING THERMOSETTING MONOMER HAS A CAGE COMPOUND OR ARYL CORE STRUCTURE, PLURALITY OF ARMS THAT ARE COVALENTLY BOUND TO THE CAGE COMPOUND OR CORE STRUCTURE INTO A POLYMER TO FORM THE LOW DIELECTRIC CONSTANT POLYMER | HONEYWELL INTERNATIONAL INC. | 2004-10-12 | — | — | US | disclosed |
| US-20040192870-A1 | Compositions and methods for thermosetting molecules in organic compositions | LAU KREISLER S (US) | 2004-09-30 | — | — | US | disclosed |
| WO-2004000909-A1 | COMPOSITIONS AND METHODS FOR THERMOSETTING MOLECULES IN ORGANIC COMPOSITIONS | HONEYWELL INTERNATIONAL INC. (US) | 2003-12-31 | — | — | WO | disclosed |
| US-20030096938-A1 | Compositions and methods for thermosetting molecules in organic compositions | LAU KREISLER (US) | 2003-05-22 | — | — | US | disclosed |
| EP-1309639-A1 | COMPOSITIONS AND METHODS FOR THERMOSETTING MOLECULES IN ORGANIC COMPOSITIONS | Honeywell International, Inc. (US) | 2003-05-14 | — | — | EP | disclosed |
| US-20030060590-A1 | Producing a low dielectric constant polymer from a thermosetting monomer that has a cage compound or aryl core structure, which is covalently bound to a plurality of arms that contain acetylenic groups | HONEYWELL INTERNATIONAL INC. | 2003-03-27 | — | — | US | disclosed |
| US-6469123-B1 | THERMOSETTING MONOMER IS INCORPORATED INTO A POLYMER TO FORM THE LOW DIELECTRIC CONSTANT POLYMER; CAGE COMPOUNDS AND CORE STRUCTURES INCLUDE ADAMANTANE, DIAMANTANE, SILICON, A PHENYL GROUP AND A SEXIPHENYLENE | HONEYWELL INTERNATIONAL INC. | 2002-10-22 | — | — | US | disclosed |
| US-20020022708-A1 | Compositions and methods for thermosetting molecules in organic compositions | HONEYWELL INTERNATIONAL INC. | 2002-02-21 | — | — | US | disclosed |
| WO-2002008308-A1 | COMPOSITIONS AND METHODS FOR THERMOSETTING MOLECULES IN ORGANIC COMPOSITIONS | HONEYWELL INTERNATIONAL INC. (US) | 2002-01-31 | — | — | WO | disclosed |