Aes-103

Aes-103

SCHEMBL27985348

O=Cc1ccc(CO)o1.[BiH3]

nearest known ligand 0.96

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.96
TSHR P16473 2/20 0.96
TDP1 Q9NUW8 4/20 0.45
G6PC1 P35575 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.41
HTT P42858 1/20 0.41
GAA P10253 1/20 0.41
KDM4E B2RXH2 6/20 0.38
POLB P06746 4/20 0.38
LMNA P02545 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
LDHA P00338 1/20 0.37
LDHB P07195 1/20 0.37
HAO1 Q9UJM8 1/20 0.37
MAPT P10636 2/20 0.35
NPC1 O15118 1/20 0.35
HSP90AA1 P07900 1/20 0.35
RAB9A P51151 1/20 0.35
TP53 P04637 1/20 0.35
HPGD P15428 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aes-103 SCHEMBL31307749 0.98
Aes-103 SCHEMBL29399464 0.96 ALDH1A1 (0.96) ALDH1A1TSHRTDP1G6PC1L3MBTL1
Aes-103 SCHEMBL17872171 0.96 ALDH1A1 (0.96) ALDH1A1TSHRTDP1G6PC1L3MBTL1
Aes-103 SCHEMBL27785806 0.96 ALDH1A1 (0.96) ALDH1A1TSHRTDP1G6PC1L3MBTL1
Aes-103 SCHEMBL1248422 0.96 ALDH1A1 (0.96) ALDH1A1TSHRTDP1G6PC1L3MBTL1
Aes-103 SCHEMBL28624601 0.96
Aes-103 SCHEMBL31307061 0.96 ALDH1A1 (0.96) ALDH1A1TSHRTDP1G6PC1L3MBTL1
Aes-103 SCHEMBL29742366 0.96 ALDH1A1 (0.96) ALDH1A1TSHRTDP1G6PC1L3MBTL1
Aes-103 SCHEMBL28986200 0.96 ALDH1A1 (0.96) ALDH1A1TSHRTDP1G6PC1L3MBTL1
Aes-103 SCHEMBL28738652 0.94 ALDH1A1 (0.92) ALDH1A1TSHRTDP1G6PC1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104119305-B A kind of method of preparing maleic anhydride by catalytic oxidation of 5-hydroxymethylfurfural DALIAN INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCES (CN) 2016-03-16 CN disclosed
CN-104119305-A Method for preparing maleic anhydride through catalytic oxidation of 5-hydroxymethylfurfural DALIAN CHEMICAL PHYSICS INST 2014-10-29 CN disclosed