Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 2/20 | 0.35 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.33 |
| ▸ | GHSR | Q92847 | 2/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13887630 | 0.82 | PDK1 (0.36) | PDK1MAP3K5MAP4K4GHSRABL1 | |
| SCHEMBL18909926 | 0.82 | PDK1 (0.36) | PDK1MAP3K5MAP4K4GHSRABL1 | |
| SCHEMBL2600246 | 0.82 | PDK1 (0.51) | PDK1MAP3K5MAP4K4 | |
| SCHEMBL16206588 | 0.82 | PDK1 (0.51) | PDK1MAP3K5MAP4K4 | |
| Hydrochloric Acid SCHEMBL1119085 | 0.80 | PDK1 (0.50) | PDK1MAP3K5MAP4K4 | |
| SCHEMBL1515598 | 0.80 | MAP4K4 (0.37) | PDK1MAP3K5MAP4K4GHSRABL1 | |
| SCHEMBL16160601 | 0.80 | MAP4K4 (0.37) | PDK1MAP3K5MAP4K4GHSRABL1 | |
| SCHEMBL1206257 | 0.80 | PDK1 (0.35) | PDK1MAP3K5MAP4K4GHSRABL1 | |
| SCHEMBL16160608 | 0.80 | MAP4K4 (0.37) | PDK1MAP3K5MAP4K4GHSRABL1 | |
| SCHEMBL15432000 | 0.77 | PDK1 (0.33) | PDK1MAP3K5MAP4K4GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104105691-A | MODULATORS OF THE G PROTEIN-COUPLED MAS RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARM INC | 2014-10-15 | — | — | CN | disclosed |