Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18461574 | 0.73 | CHRM5 (0.43) | CHRM5ADRA2CHRH3KCNH2SIGMAR1 | |
| SCHEMBL2760246 | 0.73 | CYP1A2 (0.59) | CHRM5ADRA2CCYP1A2 | |
| SCHEMBL3744984 | 0.73 | CHRM5 (0.43) | CHRM5ADRA2CHRH3KCNH2SIGMAR1 | |
| SCHEMBL2760249 | 0.73 | CYP1A2 (0.59) | CHRM5ADRA2CCYP1A2 | |
| SCHEMBL4714512 | 0.73 | CHRM5 (0.43) | CHRM5ADRA2CHRH3KCNH2SIGMAR1 | |
| SCHEMBL2831606 | 0.73 | CYP1A2 (0.59) | CHRM5ADRA2CCYP1A2 | |
| SCHEMBL18539239 | 0.73 | CHRM5 (0.43) | CHRM5ADRA2CHRH3KCNH2SIGMAR1 | |
| SCHEMBL27949712 | 0.71 | — | — | |
| SCHEMBL12568585 | 0.71 | CYP1A2 (0.62) | CHRM5ADRA2CHRH3CYP1A2 | |
| SCHEMBL6079950 | 0.71 | CYP1A2 (0.62) | CHRM5ADRA2CHRH3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104105691-A | MODULATORS OF THE G PROTEIN-COUPLED MAS RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARM INC | 2014-10-15 | — | — | CN | disclosed |