Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 4/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12568585 | 1.00 | CYP1A2 (0.62) | CYP1A2CHRM5ADRA2CHTR6HRH3 | |
| SCHEMBL4718925 | 1.00 | CYP1A2 (0.62) | CYP1A2CHRM5ADRA2CHTR6HRH3 | |
| SCHEMBL9245345 | 1.00 | CYP1A2 (0.62) | CYP1A2CHRM5ADRA2CHTR6HRH3 | |
| SCHEMBL9927921 | 1.00 | CYP1A2 (0.62) | CYP1A2CHRM5ADRA2CHTR6HRH3 | |
| SCHEMBL2831606 | 0.98 | CYP1A2 (0.59) | CYP1A2CHRM5ADRA2CHTR6 | |
| SCHEMBL2760249 | 0.98 | CYP1A2 (0.59) | CYP1A2CHRM5ADRA2CHTR6 | |
| SCHEMBL2760246 | 0.98 | CYP1A2 (0.59) | CYP1A2CHRM5ADRA2CHTR6 | |
| SCHEMBL5961386 | 0.96 | CYP1A2 (0.68) | CYP1A2CHRM5ADRA2CHTR6HRH3 | |
| SCHEMBL12568584 | 0.96 | CYP1A2 (0.68) | CYP1A2CHRM5ADRA2CHTR6HRH3 | |
| SCHEMBL12568588 | 0.96 | CYP1A2 (0.68) | CYP1A2CHRM5ADRA2CHTR6HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060004211-A1 | Preparation of 4-substituted-2-buten-4-olides from mucohalic acids | WARNER-LAMBERT COMPANY LLC | 2006-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004211-A1 | Preparation of 4-substituted-2-buten-4-olides from mucohalic acids | MUC1, FUT6, FUT5 | CYP1A2 2409/4885CHRM5 2736/4885ADRA2C 775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.