SCHEMBL27985693

SCHEMBL27985693

Cc1cccc(N=C=O)c1F

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.61
TRPA1 O75762 1/20 0.44
GABRA1 P14867 1/20 0.38
GABRB2 P47870 1/20 0.38
ALDH1A1 P00352 2/20 0.34
HPGD P15428 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
ACHE P22303 1/20 0.33
CYP1A2 P05177 1/20 0.31
CYP2A6 P11509 1/20 0.31
USP2 O75604 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA7 P43166 1/20 0.30
CA9 Q16790 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28210896 0.85 CYP3A4 (0.60) CYP3A4TRPA1GABRA1GABRB2ALDH1A1
SCHEMBL28564133 0.82 CYP3A4 (0.50) CYP3A4TRPA1GABRA1GABRB2ALDH1A1
SCHEMBL29440559 0.79 CYP3A4 (0.79) CYP3A4TRPA1GABRA1GABRB2ALDH1A1
SCHEMBL93192 0.79 CYP3A4 (0.79) CYP3A4TRPA1GABRA1GABRB2ALDH1A1
SCHEMBL29662014 0.79 CYP3A4 (0.54) CYP3A4TRPA1GABRA1GABRB2ALDH1A1
SCHEMBL1595410 0.79 CYP3A4 (0.54) CYP3A4TRPA1GABRA1GABRB2ALDH1A1
SCHEMBL93287 0.79 CYP3A4 (0.64) CYP3A4TRPA1GABRA1GABRB2ALDH1A1
SCHEMBL29541215 0.79 CYP3A4 (0.64) CYP3A4TRPA1GABRA1GABRB2ALDH1A1
SCHEMBL20145 0.78 CYP3A4 (0.63) CYP3A4TRPA1GABRA1GABRB2ALDH1A1
SCHEMBL30520271 0.78 CYP3A4 (0.63) CYP3A4TRPA1GABRA1GABRB2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109536135-A A kind of marble tile anti-pollution antilubricant and preparation method thereof 山东中佳生活服务有限公司 2019-03-29 CN disclosed
CN-102731814-B Be suitable for the composition comprising specific amino formate compounds preparing polyurethane foam EVONIK DEGUSSA GMBH (DE) 2016-03-09 CN disclosed
CN-101875961-B Diaryl and arylheteroaryl urea derivatives as modulators of the 5-HT2A serotonin receptor useful for the prophylaxis and treatment of disorders related therto ARENA PHARM INC 2015-01-07 CN disclosed